[ RadSafe ] References: Radiation induced immune response DETERS spread of cancer

Tue Aug 29 13:36:49 CDT 2006

Dr. Long,
Where does it mention cancer in the posting below your
comments?  Did you send the wrong information?  Are
you making a claim that was not indicated by the
authors of the posting?

Also, can you cite a reference where it can be
demonstrated that "radiation blocks 9 ORDERS of
magnitude more mutations than it causes."  That is an
astonding number and should be supported by astonding
proof.  If so, how does one reconcile the fact that
49% of the population will develop a cancer in their
life-time?

--- howard long <hflong at pacbell.net> wrote:

>   Health Physicists,
>    
>   The following recent exchange on Rad-Sci will help
> rad-safe participants to position themselves for the
> coming use of 1 to 10 rads to prevent cancer.
> Pollycove and Feinendigan have shown in cell and
> mouse studies that radiation blocks 9 ORDERS of
> magnitude more mutations than it causes. The
> speculations presented by Jacobus below show the
> stimulus, but not the 1,000,000,000 x biologic
> defense response!     
>   Howard Long
>    
>   From: ?lt;i>howard long <hflong at pacbell.net>
> To: ?lt;i>christoph.koestinger at gmx.net,
> rad-sci-l at WPI.EDU
> CC: ?lt;i>"'Dietrich Harder'" <d.b.harder at gmx.de>
> Subject: ?lt;i>Radon, anti-inflammatory medicines
> and the immunesystem
> Date: ?lt;i>Mon, 3 Jul 2006 09:40:09 -0700 (PDT)
> 
> Thank you, Dietrich Harder and Christopher
> Koestinger for this biologic explanation of radon
> improvement of arthritis. Radon certainly is safer,
> as you use it, than our non-steroidal
> antiinflammatory drugs and corticoids, as we must
> use them.
> ?
> ?lt;/div> ?lt;br> This should be publicized to
> enable use of radon by a propagandized public.
> ?
> Radon removers and regulators disinform to
> perpetuate their useless and damaging occupations.
> ?
> ?lt;/div> ?lt;br> Howard Long, family doctor,
> epidemiologist
> 
> Christoph Köstinger <christoph.koestinger at gmx.net>
> wrote:
> ?
> 
>   ??lt;br> ?
> I forwarded the below discussion to Prof. Harder,
> University Goettingen, who is one of 
> the authors of the recent published book "Radon als
> Heilmittel" and I would like to forward his answer
> now.
> ?
> Christoph Koestinger
> Gasteiner Heilstollen, Austria
> ?lt;br> ?lt;/div> ?lt;br> Dear friends,
> ?lt;br> thank you for sending me some questions
> concerning the treatment of rheumatic arthritis with
> radon. According to present insight, the
> anti-inflammatory action mechanism of alpha
> particles, mediated by low alpha-particle doses in
> epithelial tissues, is a three-stage mechanism:
> ?lt;br> a) Deposition of the radon daughter products
> in the corneal layer of the skin (bath treatment,
> treatment in caves) respectively in the lung
> epithelium (treatment in caves). The enhanced 
> solubility of radon gas in fatty tissues is true,
> but does only play a marginal role.
> ?
> b) Alpha-particle induced production of apoptotic
> cells in the epithelia at low doses, supported by
> the bystander effect.
> ?lt;br> c) Mediation of an anti-inflammatory immune
> response, triggered by the phagocytosis of the
> apoptotic cells by dendritic cells, e.g. the
> Langerhans cells. This process can be called a
> modification of the immune response rather than an
> enhancement of the immune response. The word
> "enhancement" however is not incorrect when referred
> to the enhanced maturation of immature dendritic
> cells and the enhanced activation of
> anti-inflammatory cytokines.
> ?lt;br> The applied doses are so low that a complete
> annual treatment course does not more than double
> the normal natural radiation exposition of the human
> body, when 
> expressed in terms of the effective dose per year.
> ?
> The great advantage of the anti-inflammatory
> treatment with radon lies in the long-time reduction
> of the administration of anti-inflammatory drugs
> which have numerous side effects.
> ?lt;br> I have described this mechanism in a chapter
> of the book "Radon als Heilmittel", edited by RADIZ
> Schlema and published by Dr.Kovac, Hamburg (ISSN
> 1435-6309, ISBN 3-8300-1768-5). The special question
> how the alpha particles, emitted by radon daughters
> deposited deep in the corneal layer of the skin, can
> reach epithelial cell layers containing Langerhans
> cells is being treated in biophysical experiments of
> Prof.
> ?lt;br> von Philipsborn, and the results will be
> presented in a specialized scientific symposium, the
> "4th Biophysikalische Arbeitstagung" in Bad Schlema
> (Germany), Sept. 22 - 
> 24, 2006; informations by our bureau
> radizev at t-online.de.
> ?
> With kindest regards, Dietrich Harder.
> 
> 
> John Jacobus <crispy_bird at yahoo.com> wrote:  Dr.
> Long,
> Your preferences are your choices. I think that
> researchers who study cancer should not be
> discounted
> even if they do not studies do not align with your
> beliefs. Obviously you need to keep up with the
> research literate. Macrophages are not dendritic
> cells, and as a physician I would think that you
> would
> know that. My point is that the biology of cancer is
> very complex and treatments are not as simplistic as
> you think.
> 
> Again, you can only quote the speculations of Dr.
> Chen, who even acknowledges that his work was never
> followed up. 
> 
> --- howard long wrote:
> 
> > Prof Dietrich Harder of U Goettingen describes the
> > mechanism recently on rad-sci:
> > 
> > "- production of apoptotic cells in the epithelia
> > at low doses, supported by the bystander effect.
> > Mediation of an anti-inflammatory immune response,
> > triggered by the phagocytosis of the apoptotic
> cells
> > by dendritic cells, e.g. the Langerhans cells.
> This
> > process can be called a modification of the immune
> > response rather than an enhancement of the immune
> > response. The word "enhancement" however is not
> > incorrect when referred to the enhanced maturation
> > of immature dendritic cells and the enhanced
> > activation of anti-inflammatory cytokines.
> > The applied doses are so low that a complete
> annual
> > treatment course does not more than double the
> > normal natural radiation exposition of the human
> > body, when 
> > expressed in terms of the effective dose per year"
> > 
> > I was referred to this by Prof Feinendigan who,
> > with Prof Pollycove has done the most in this
> area,
> > as in The Biologic and Epidemiologic Basis for
> > Radiation Hormesis, presented to and critiqed by
> > Doctors for Disaster Preparedness.
> > 
> > Far from worsening cancer patients, low dose
> > radiaion
> > stimulation of apoptosis, phagocytosis and the
> > immune system generally, brings healing - NOT the
> > more rapid cancer growth implied by this Jacobus
> > selection, as could be found in numerous
> references
> > through Muckerheides compendium.
> > For prevention, see,
> > Is Chronic Radiation anEffective Prophylaxis
> > Against Cancer? 
> > Chen, WL, Luan, YC, et al Journal Am Physicians
> > and Surgeons 9:1:6-10
> > 
> > Howard Long MD MPH
> > 
> > John Jacobus wrote:
> > One of the arguements used to tout the benefits of
> > low
> > dose ionizing radiation is that it enhances immune
> > response. I thought the following was interesting.
> > -----------------------
> > >From the NYT Health section
> >
>
http://www.nytimes.com/2006/08/15/health/15meta.html?ei=5070&en=43242bd64ec6e9b0&ex=1156651200&pagewanted=all
> > 
> > Scientists Begin to Grasp the Stealthy Spread of
> > Cancer 
> > 
> > By LAURIE TARKAN
> > Published: August 15, 2006
> > 
> > . . .
> > Researchers are looking at a number of events that
> > occur in the microenvironment that give a cancer
> > cell
> > a leg up as soon as it arrives. These changes
> > involve
> > both normal cells that reside in that tissue and
> the
> > body’s roaming immune cells. 
> > 
> > “The tumor cells co-opt these cells to act in a
> way
> > that’s conducive for the growth of the
> metastasis,”
> 
=== message truncated ===

+++++++++++++++++++
>From an article about physicians doing clinical studies: 

"It was just before an early morning meeting, and I was really trying to get to the bagels, but I couldn't help overhearing a conversation between one of my statistical colleagues and a surgeon.

Statistician: "Oh, so you have already calculated the P value?"

Surgeon: "Yes, I used multinomial logistic regression."

Statistician: "Really? How did you come up with that?"

Surgeon: "Well, I tried each analysis on the SPSS drop-down menus, and that was the one that gave the smallest P value"."

-- John
John Jacobus, MS
Certified Health Physicist
e-mail:  crispy_bird at yahoo.com

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