[ RadSafe ] Re: Tolerance Dose

Prof. Dr.Wolfgang Doerr Wolfgang.Doerr at tu-dresden.de
Tue Apr 28 17:57:32 CDT 2009

In clinical radiobiology/radiation oncology, the "tolerance dose" is  
the dose at which - for a certain organ and a defined (clinically  
relevant) endpoint - the expected incidence is 0. Alternatively, it  
can be the dose at which a certain incidence of the defined endpoint  
(e.g. 5%) is observed.
Prof. Dr. Wolfgang Dörr

Strahlenbiologisches Labor
Klinik für Strahlentherapie und Radioonkologie
Medizinische Fakultät Carl Gustav Carus

Fetscherstr. 74, PF58
D-01307 Dresden
Tel 0351/458-3390
Fax 0351/458-4347

Zitat von "Strom, Daniel J" <strom at pnl.gov>:

> Tolerance dose was a radiation protection concept in the first half   
> of the 20th century. See
> Cantril ST, Parker HM. 1945. "The Tolerance Dose." MDDC-1100;   
> CH-2812. Oak Ridge, Tennessee: U.S. Atomic Energy Commission.   
> Bitmap; 1.59 Mbytes.   
> http://www.pnl.gov/bayesian/refs/Cantril1945_MDDC-1100_CH-2812_Tolerance_Dose.pdf accessible from http://www.pnl.gov/bayesian/refs/classics.htm   
> .
> - Dan Strom
> The opinions expressed above, if any, are mine alone and have not   
> been reviewed or approved by Battelle, the Pacific Northwest   
> National Laboratory, or the U.S. Department of Energy.
> Daniel J. Strom, Ph.D., CHP
> Energy and Environment Directorate, Pacific Northwest National Laboratory
> Mail Stop K3-56, PO BOX 999, Richland, Washington 99352-0999 USA
> Overnight: Battelle for the U.S. DOE, 790 6th St., Richland WA 99354  
>  ATTN: Dan Strom K3-56
> Telephone (509) 375-2626 FAX (509) 375-2019 mailto:strom at pnl.gov
> Radiological Sciences and Engineering: http://radiologicalsciences.pnl.gov/
> Brief Résumé: http://www.pnl.gov/bayesian/strom/strombio.htm
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