[ RadSafe ] 'How Low Doses Of Radiation Can Cause Heart DiseaseAnd Stroke'
דב בריקנר
brickner at smile.net.il
Sat Oct 24 05:15:29 CDT 2009
The answer appears in the discussion part ; "The doses used here are
moderate (10 mGy/day), such as might occur in occupationalexposure settings,
and would account for the observed radiationassociated excess risk that has
been seen in various groups of nuclear workers [10–14]."
Personally I don't consider a 10mGy/day dose as low and certainly it is not
in the occupational exposure range! Continuous exposure to such a dose may
end with myelodyspalastic syndrome before the atherogenic process will
become clinically relevant...
Dov Brickner MD
Beer-Sheva Israel
-----Original Message-----
From: radsafe-bounces at radlab.nl [mailto:radsafe-bounces at radlab.nl] On Behalf
Of Harry Reynolds
Sent: Friday, October 23, 2009 9:12 PM
To: Brennan, Mike (DOH); Radsafe
Subject: RE: [ RadSafe ] 'How Low Doses Of Radiation Can Cause Heart
DiseaseAnd Stroke'
"Below 0.5 Gy" does not relate to occupational (<0.05 Gy) or background
(<0.005 Gy).
What dose ranges are they referring to?
Harry Reynolds
ASRSO
ENERGYSOLUTIONS
801-649-2219 Desk
801-349-9036 Cell
-----Original Message-----
From: radsafe-bounces at radlab.nl [mailto:radsafe-bounces at radlab.nl] On
Behalf Of Brennan, Mike (DOH)
Sent: Friday, October 23, 2009 12:48 PM
To: Radsafe
Subject: RE: [ RadSafe ] 'How Low Doses Of Radiation Can Cause Heart
DiseaseAnd Stroke'
This should be fairly easy to verify by looking at long term residents
of areas with different background levels, and seeing if there is a
trend, once all confounding issues are accounted for.
-----Original Message-----
From: radsafe-bounces at radlab.nl [mailto:radsafe-bounces at radlab.nl] On
Behalf Of Monty Charles
Sent: Friday, October 23, 2009 8:57 AM
To: Mark Ramsay; srp-uk at yahoogroups.com; Radsafe;
HASNET-RAD at JISCMAIL.AC.UK
Subject: [ RadSafe ] 'How Low Doses Of Radiation Can Cause Heart Disease
AndStroke'
I don't think one can be complacent about this. Evidence is slowly
mounting
in support a low dose effect (below 0.5Gy) for non-cancer diseases. One
factor which led ICRP (Publication 103) and UNSCEAR (2006) not to
include non-cancer risks in their general low dose risk estimates was
the
lack of an underlying biological mechanism. The paper of Little et al is
worth
a read. Their mathematical model has a reasonable biological basis and
predicts LNT for cardiovascular disease. The authors point out the
limitations of the the model - but it has the great virtue of being
testable by
in-vitro, animal or human studies. It gains plausibility by predicting
excess
relative risk values in line with observed values from a range of
epidemiology studies. The mathematics will be intractable to many but
the
table which compares model predictions with radiation epidemiology data
is
clear.
Monty Charles
*******************************
> Hi Mark
>
> Thank you for sending the link to the article. It was not a new
> finding. RERF has noted it among the A-bomb
> survivors. It appears that the effect is so small that it is
> unlikely to influence the magnitude of the currently
> accepted risk estimates
>
> Regards
> K S Parthasarathy
>
> ________________________________
> From: Mark Ramsay <mark.ramsay at ionactive. co.uk>
> To: srp-uk at yahoogroups.com; Radsafe <radsafe at radlab.nl>;
> HASNET-RAD at JISCMAIL.AC.UK
> Sent: Fri, 23 October, 2009 19:19:17
> Subject: [ RadSafe ] 'How Low Doses Of Radiation Can Cause Heart
> Disease And Stroke'
>
> Hello all.
>
> 'How Low Doses Of Radiation Can Cause Heart Disease And Stroke'
>
> Not 'new news' - but latest paper published today - (cat and
> pigeons
> comes to mind if this is accepted).
>
> News article found here: http://tiny.cc/CP9Ha
>
> Full publication of paper found here http://tiny.cc/ssgST
>
> Regards
>
> Mark
>
> Mark Ramsay
> Radiation Protection Adviser
>
> Email: mark.ramsay at ionactive. co.uk
> Web: www.ionactive.co.uk
>
> Ionactive on Twitter
> www.twitter.com/ionactive
>
> Ionactive Blog
> www.ionactive.co.uk/blog
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Dr Monty Charles
Reader in Radiation Physics
School of Physics & Astronomy
University of Birmingham
Edgbaston
Birmingham B15 2TT, UK
Tel +44(0)121 414 3483
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