[ RadSafe ] Chemical Laboratory Safety and Security: A Guide to Prudent Chemical Management

Cary Renquist cary.renquist at ezag.com
Fri Dec 3 18:00:22 CST 2010

Good breadth -- not a lot of depth for basic laboratory safety/security
including engineering controls, lab design, etc.
Free ~280 page pdf for download -- also available as book with CD.

Cary.renquist at ezag.com

National Academy of Sciences:
Board on Chemical Sciences and Technology - bcst 

Chemical Laboratory Safety and Security: A Guide to Prudent Chemical

Good safety and security procedures can lead to greater productivity,
efficiency, savings, and most importantly, greater sophistication and
cooperation. Improving safety and security is mistakenly seen as
inhibitory, because of lack of understanding of safety and security
procedures, cultural barriers, lack of skills, and financial
constraints. Chemical Laboratory Safety and Security A Guide to Prudent
Chemical Management and accompanying toolkit will assist chemists in
developing countries to overcome the barriers they face and increase the
level of safety and security in their labs through improved chemicals
management and following the best laboratory practices possible.

Reference book

Chemical Laboratory Safety and Security: A Guide to Prudent Chemical

Toolkit Items

* Quick guide for laboratory managers (brochure format)
* Quick guide for laboratory managers (page-by-page format)
* Executive summary to share with institutional leaders (brochure
* Executive summary to share with institutional leaders (page-by-page
* Instructor's guide, forms, and signs to photocopy and distribute
* Preplanning reference cards to distribute to laboratory personnel
* Helpful reminder signs for posting in the laboratory

Arabic- Coming Soon
French- Coming Soon
Indonesian- Coming Soon

Executive Summary 1
Why Are Chemical Safety and Security Important for Your Institution? 2
Fostering a Culture of Chemical Safety and Security 2
Responsibility and Accountability for Laboratory Safety and Security 3
Types of Hazards and Risks in the Chemical Laboratory 4
Enforcing Laboratory Safety and Security 7
Finding and Allocating Resources 8
What Can You Do to Improve Chemical Safety and Security? 9
Ten Steps to Establish a Safety and Security Management System 9
Chemical Safety and Security at the Laboratory Level 11
1 The Culture of Laboratory Safety and Security 13
2 Establishing an Effective Chemical Safety and Security
Management System 15
2.1 Introduction 16
2.2 Whose Job Is It? Responsibility for Laboratory Safety and Security
2.3 Ten Steps to Creating an Effective Laboratory Chemical Safety and
Security Management System 19
3 Emergency Planning 25
3.1 Introduction 26
3.2 Developing an Emergency Preparedness Plan 26
3.3 Assessing Laboratory Vulnerabilities 27
3.4 Identifying Leadership and Priorities 27
3.5 Creating a Plan 28
3.6 Emergency Training 35
4 Implementing Safety and Security Rules, Programs, and Policies 37
4.1 Introduction 38
4.2 Essential Administrative Controls 38
4.3 Inspections 39
4.4 Incident Reporting and Investigation 40
4.5 Enforcement and Incentive Policies 40
4.6 Best Practices of a Performance Measurement Program 41
4.7 Twelve Approaches to Following Best Practices 42
5 Laboratory Facilities 47
5.1 Introduction 48
5.2 General Laboratory Design Considerations 48
5.3 Laboratory Inspection Programs 50
5.4 Laboratory Ventilation 50
5.5 Special Systems 54
5.6 Ventilation System Management Program 55
6 Laboratory Security 59
6.1 Introduction 60
6.2 Security Basics 60
6.3 Establishing Levels of Security 61
6.4 Reducing the Dual-Use Hazard of Laboratory Materials 63
6.5 Establishing Information Security 64
6.6 Conducting Security Vulnerability Assessments 65
6.7 Creating a Security Plan 66
6.8 Managing Security 67
6.9 Regulatory Compliance 68
6.10 Physical and Operational Security 69
7 Assessing Hazards and Risks in the Laboratory 71
7.1 Introduction 73
7.2 Consulting Sources of Information 73
7.3 Evaluating the Toxic Risks of Laboratory Chemicals 74
7.4 Assessing the Toxic Risks of Specific Laboratory Chemicals 75
7.5 Assessing Flammable, Reactive, and Explosive Hazards 80
7.6 Assessing Physical Hazards 88
7.7 Assessing Biohazards 90
8 Managing Chemicals 91
8.1 Introduction 92
8.2 Green Chemistry for Every Laboratory 92
8.3 Purchasing Chemicals 95
8.4 Inventory and Tracking of Chemicals 97
8.5 Storage of Chemicals 98
8.6 Transfer, Transport, and Shipment of Chemicals 104
9 Working with Chemicals 105
9.1 Introduction 107
9.2 Careful Planning 107
9.3 General Procedures for Working with Hazardous Chemicals 108
9.4 Working with Substances of High Toxicity 120
9.5 Working with Biohazardous Materials 122
9.6 Working with Flammable Chemicals 123
9.7 Working with Highly Reactive or Explosive Chemicals 125
10 Working with Laboratory Equipment 135
10.1 Introduction 137
10.2 Working with Electrically Powered Equipment 137
10.3 Working with Compressed Gases 139
10.4 Working with High and Low Pressures and Temperatures 143
10.5 Using Personal Protective, Safety, and Emergency Equipment 148
11 Managing Chemical Waste 151
11.1 Introduction 152
11.2 Identifying Waste and Its Hazards 153
11.3 Collecting and Storing Waste 154
11.4 Treatment and Hazard Reduction 158
11.5 Disposal Options 160

A. A.1. Example List of Chemicals of Concern 165
B. B.1. Sources of Chemical Information 175
C. C.1. Types of Inspection Programs 181
C.2. Elements of an Inspection 184
C.3. Items to Include in an Inspection 186
D. D.1. Design Considerations for Casework, Furnishings, and Fixtures
D.2. Laboratory Engineering Controls for Personal Protection 190
D.3. Laboratory Hoods 192
D.4. Maintenance of Ventilation Systems 195
E. E.1. Developing a Comprehensive Security Vulnerability Assessment 197
F. F.1. Assessing Routes of Exposure for Toxic Chemicals 201
F.2. Assessing Risks Associated with Acute Toxicants 204
F.3. Flash Points, Boiling Points, Ignition Temperatures, and
Flammable Limits of Some Common Laboratory Chemicals 206
F.4. Chemicals That Can Form Peroxides 207
F.5. Specific Chemical Hazards of Select Gases 209
G. G.1. Setting Up an Inventory 211
G.2. Examples of Compatible Storage Groups 214
H. H.1. Personal Protective, Safety, and Emergency Equipment 215
H.2. Materials Requiring Special Attention Due to Reactivity,
Explosivity, or Chemical Incompatibility 221
I. I.1. Precautions for Working with Specific Equipment 229
I.2. Guidelines for Working with Specific Compressed
Gas Equipment 237
I.3. Precautions When Using Other Vacuum Apparatus 240
J. J.1. How to Assess Unknown Materials 242
J.2. Procedures for Laboratory-Scale Treatment of Surplus and
Waste Chemicals 246

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