[ RadSafe ] RadSafe Digest, Vol 343, Issue 1

Earley, Jack N Jack_N_Earley at RL.gov
Fri Jul 2 12:26:16 CDT 2010

Parathasarathy wrote:

"The finding that the process of repairing DNA damage itself causes more mutations is worrying. No wonder one may have to continue to accept LNT concept for the time being as a precautionary approach."

As a process of adaptation, some proteins are activated in times of stress that deliberately generate "random" errors in the repair process. Those that are viable continue to reproduce, and the proteins are then deactivated.

I don't see the connection for accepting a faulty model; it seems to be a non sequitur. Other animals seem to recognize much more quickly than do humans when a faulty model should be abandoned (a lesson I've been slow to learn). A comparison is that a fly will probably escape from a clear bottle that has its closed end facing a window; a bee probably won't.

Jack Earley
Sr. Health Physicist

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