[ RadSafe ] DOE workshop presentation and DDP questioning

[Howard]

Bobby's presentation at DDP should include what he writes below.
All attending (Radsafers invited) can question him, like the other speakers listed:
Howard Long 
Friday, July 15 at 7:00pm - July 17 at 5:00pm
Location	
Sheraton Albuquerque Airport
2910 Yale Blvd SE
Albuquerque, NM
Created By	
Doctors For Disaster Preparedness, Adrienne Snavely
More Info	
Tour to Los Alamos Labs on July 15 is FULL

Speakers include:
Willie Soon, PhD
Jay Lehr, PhD
Bobby Scott
Richard Allen Keen, PhD
Art Robinson, PhD
Greg Canavan, PhD
William Gray, PhD
Christopher Essex
Donald Miller, MD
Allen Brodsky, PhD
Craig Idso
Steven Hatfill, MD
Howard Hayden
Tom DeWeese
Fred Singer, PhD

Check out videos from past meetings at www.ddponline.org

Room rate is $89. Please call 505-843-7000 and ask for the DDP room block.

Registration Prices for the meeting include welcome reception, two breakfasts, two lunches, and the banquet.
1st Registrant: $250
Additional Family Members/Guests: $200
Register by Mail or online at:
http://www.ddponline.org/2011-meeting-registration/
On May 16, 2011, at 3:58 PM, "Scott, Bobby" <BScott at lrri.org> wrote:

> Hi All:
> 
> 
> In case it may be of interest, my presentation given last week at the
> DOE Low Dose Radiation Research Program Investigators' Workshop X is
> available at the link below:
> 
> 
> "Differential epigenetic changes in the lung after low and high
> carcinogen doses and implications for designing molecular epidemiology
> and other studies of radiation-induced lung cancer"
> 
> http://dspace.lrri.org:8080/xmlui/handle/123456789/1064
> 
> 
> In the presentation, I point out the need for new terminology related to
> discussing consequences to humans from low-level exposure to low- or
> low- plus high-LET radiation (e.g., radiation exposure in the home from
> radon progeny).  I introduce the adaptive protection function, A(x), and
> benefit function B(x) = 1 - exp[-A(x)], which respectively correspond to
> the high-dose hazard function H(x) and related risk function R(x) = 1-
> exp[-H(x)], widely used in risk assessment. B(x) is the probability of
> radiation activated natural protection (ANP) against cancer (e.g.,
> against smoking-related lung cancer). The independent variable x is the
> dose or exposure level.  Interestingly, for low-level exposure to radon
> progeny and for lung cancer, the benefit B(x) can be close to 1 (e.g.,
> for protecting against smoking-related lung cancer) while the risk R(x)
> for radiogenic cancer is close to zero.  This indicates that the
> probability B(x) can be orders of magnitude greater than the probability
> R(x), while much of the current focus is unfortunately on R(x) (usually
> under the invalid LNT hypothesis). At the EPA's action level of 4
> picocuries/L (approximately 150 Bq/cubic meter), B(x) = 1 for ANP
> against sporadic lung cancer (i.e., everyone expected to benefit from
> natural protection against lung cancer). The natural protection when
> maintained over a prolonged period prevents a future cancer with
> probability PROFAC (the protection factor, a population average which
> varies with different populations). PROFAC is the average over the
> at-risk population of individual-specific protection factors "profac".
> For x close to zero, cancer relative risk (RR; population average) is
> given by RR = 1 - B(x)PROFAC (hormetic zone where RR < 1). For large
> values of x, B(x) goes to zero (no benefit) and H(x) can be >> 1
> (serious hazard with R(x) close to 1).
> 
> 
> Bobby R. Scott
> 
> Senior Scientist
> Lovelace Respiratory Research Institute
> 2425 Ridgecrest Drive SE
> Albuquerque, NM 87108 USA
> 
> 
> 
> _______________________________________________
>