[ RadSafe ] High Dose Antedotes
Otto G. Raabe
ograabe at ucdavis.edu
Mon Nov 28 13:14:11 CST 2011
JAMES FORD PIX11.com
7:45 p.m. EST, November 26, 2011
NEW YORK (PIX11)
In a city that's been the victim of one of the
world's largest terrorist attacks, and which is
within a fifty mile radius of both the Indian
Point and Oyster Creek nuclear power plants, one
of the greatest fears in New York is of a
radioactive emergency caused by terrorism or by
accident. Now, however, a breakthrough has
emerged to treat the devastating, fatal effects of such an incident.
"[It's] a groundbreaking study," Dr. Ofer Levy,
45, of the Children's Hospital, Boston and
Medical School, told PIX11 News in an exclusive
New York interview about a two-drug treatment
that in clinical trials appears to create
conditions that could help people survive some of
the worst known health conditions. "[Such as] a
nuclear leak, or war, terrorism or other sources of radiation," Levy said.
The newly released results of the five-year study
Dr. Levy conducted with Dr. Eva Guinan of the
Center are remarkable. In the study, they
combined two substances -- fluoroquinolone, an
antibiotic related to Cipro, which is taken
orally, and a protein called
bactericidal/permeability-increasing protein, or BPI.
When that combination of substances was
administered in trial after trial on mice that
had been exposed to radiation multiple times the
lethal level, not only did the mice survive,
according to Dr. Levy, "We found dramatically
improved survival in the animals who got the combination."
In other words, the health of the mice improved.
Also, the two substances used in the study have
not only been used on mice, they have been used
separately, and safely, on humans for years. The
study provided the first comprehensive results of
fluoroquinolone and BPI being used together, and
what's more, they were administered a full 24
hours after the radiation exposure, and still provided unprecedented results.
"That you can give them so late and that they
both have a safety track record in humans," Dr.
Levy told PIX11 News, "We believe makes this a ground breaking study."
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