[ RadSafe ] Fwd: LNT

[James Salsman]

[Jeff, I know you're not permitting my posts on RADSAFE recently, but
I hope you will please make an exception for this one since Dr. Raabe
replied to me cc'ing the list.]

---------- Forwarded message ----------
From: James Salsman <jsalsman at gmail.com>
Date: Thu, Sep 29, 2011 at 2:38 PM
Subject: Re: [ RadSafe ] LNT
To: "Otto G. Raabe" <ograabe at ucdavis.edu>


On Thu, Sep 29, 2011 at 1:57 PM, Otto G. Raabe <ograabe at ucdavis.edu> wrote:
> At 10:41 AM 9/29/2011, James Salsman wrote:
>
> How do you control for confounding effects when the internal emitters
> are chemical genotoxins?
>
> Give me one example. I don't know of any radionuclides that are also
> chemical genotoxiicants in typical exposure quantities even though I have
> been studying radiation effects for many years.

Uranium e.g. http://toxsci.oxfordjournals.org/content/89/1/287.abstract
or http://www.ncbi.nlm.nih.gov/pubmed/19914362

> If chemical toxicity is a factor, any observed effect might be attributed to
> the ionizing radiation.

That's absolutely true.  I am not sure there's a way to separate the
causes (although that pubmed reference using different isotopes might
be one way.)  Few people know that uranyl ion is used to stain DNA for
x-ray and visible microscopy.