[ RadSafe ] What does it mean to say that something causes 16%of cancers?
mohan.doss at fccc.edu
Fri May 11 15:20:56 CDT 2012
I agree with you that cancers are symptoms of an underlying condition.
A few points to note:
1. About 45% of the population is likely to be diagnosed with cancer in
their lifetime (ACS estimate, e.g.). You may think the remaining 55% of
the population do not have cancer. However, when autopsies are
performed, you are likely to find cancer cells in almost all of them (if
they are well into their old age).
2. When the immune system is suppressed, e.g. in AIDS patients or organ
transplant patients, the cancer risk goes up by a factor of about 2.4.
Thus, the 55% of population that you thought do not have cancer will
have cancer, if we suppress their immune system. We can probably
extrapolate this backwards and say that if you improved the immune
system, you would decrease the cancer, and maybe eliminate the cancer
altogether. One method of boosting the immune system is regular
moderate vigorous exercise. This is known to reduce cancer incidence
and mortality for many types of cancers. Another method of boosting the
immune system is through low dose radiation. Low dose radiation is
known to reduce cancers in controlled studies in animal models. For
humans, though reduction in cancers has been observed from low dose
radiation in many retrospective studies, the potential confounding
factors make it difficult to convince all scientists (or the general
public) who are scared of the low dose radiation. We need controlled
clinical trials to determine conclusively the effectiveness of low dose
radiation in preventing cancers.
Thus the underlying condition that causes (most) clinical cancers is
deficiency in the immune system (in my opinion, based on the above
points). So long as we don't recognize this factor, and deal with it,
we are not likely to succeed in conquering cancer. Thus our current
radiation safety system based on the LNT model (which completely ignores
the effect of low dose radiation on the immune system) is a major
failure of our current scientific society. If what I have said here is
shown to be true in the future, people are going to refer to our present
days as the Dark Ages with regard to radiation, and wonder how we did
not recognize the importance of the immune system in preventing cancer
for so long (~40 years).
With best regards,
Mohan Doss, Ph.D., MCCPM
Medical Physicist, Diagnostic Imaging,
Fox Chase Cancer Center, R427
333 Cottman Avenue,
Philadelphia, PA 19111-2497.
Phone: 215 214-1707
Fax: 215 728-4755
E-mail: Mohan.Doss at fccc.edu
On 5/11/2012 2:28 PM, Brennan, Mike (DOH) wrote:
> More and more I am coming to think "cancer" is like "fever", in that it
> describes a symptom, rather than a disease. I think we are moving past
> being limited to treating the symptom to understanding the various
> things that can cause it.
> A great irony is that the population has been taught to fear radiation
> as the cause of cancer, when it is actually an absolutely necessary to
> in understanding and treating cancers.
> -----Original Message-----
> From: radsafe-bounces at health.phys.iit.edu
> [mailto:radsafe-bounces at health.phys.iit.edu] On Behalf Of Clayton J
> Sent: Friday, May 11, 2012 11:10 AM
> To: radsafe at health.phys.iit.edu
> Cc: Cary.renquist at ezag.com
> Subject: Re: [ RadSafe ] What does it mean to say that something causes
> 16%of cancers?
> Cary Renquist wrote:
> "Cancer is more like poverty (caused by a number of events
> throughout one's life, some inherited and some not) rather than
> (caused by a very specific infection delivered via mosquito)."
> Except that sometimes cancer is like malaria:
> Certain strains of human papilloma virus cause cervical cancer.
> virus genes have been identified which are found to be spliced into the
> tumor cells DNA causing them to proliferate while evading immune defense
> Other cancers have also been found to be caused by viruses.
> Clayton J. Bradt
> Principal Radiophysicist
> NYS Dept. of Health
> Biggs Laboratory, Room D486A
> Empire State Plaza
> Albany, NY 12201-0509
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