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Depleted Uranium and Leukemia



To Radsafe.
                                IS DU REALLY THE CAUSE?

There have been several recent postings on the subject of possible excess of cancers including leukaemia in military personnel who have served in the Gulf war or most recently in peace keeping operations in the Balkans.

The public media has jumped on to the depleted uranium story (DU) as THE CAUSE.  The Rand report which received much favourable comment on this list would indicate that DU is unlikely to have a role in the aetiology of cancer or even to be a significant cause of human ill health.

Since about 1988 Professor L Kinlen and his group in the UK have published numerous epidemiological studies suggesting that when large groups of people are assembled from different areas to work say in a major construction site there is an exchange of microbiological material including cancer inducing viruses.

Published examples given for this a hypothesis are many:-
 
·       Evidence for an infective cause. Lancet 10th December 1988; Page 1323-1326.

·       Population Mixing in New Towns. Lancet 1990; 336: 577-82.

·       Nuclear establishments in West Berkshire. Brit J Cancer 1991;64:549-554.

·       North sea oil industry in Scotland. Brit Med J 1993; 306 : 743- 748.

·       Wartime evacuation of children in England and Wales. Brit Med J 1994;309:1197-1202.

·       Guest Editorial.  Brit J Cancer 1995; 71:1-5.

·       Sellafield nuclear site.   Brit Med J 1995; 310: 763-768

·       Editorial:      Cancer causes and Control 1998; 9: 237-239.

·       Dickinson HO and Parker L. Brit J Cancer 1999; 81: 144-151

·       Doll R.   Brit J Cancer 199; 81 : 3-5

As far as I am aware the causative agent or agents are unknown. Doll has pointed that identifying the causative agent may prove to be exceptionally difficult.

I would suggest that the assembly of large international armies and mixing with local population is an analogous situation and could be consistent with the Kinlen hypothesis.

Ivor Surveyor [isurveyor@vianet.net.au]
Emeritus Consultant Physician
Nuclear Medicine
Royal Perth Hospital