Fwd: I-131 Thyroid CA Therapy Question

[Chris Alston <alstonc@odrge.odr.georgetown.edu>]

>From: "Greg Madison, MS" <gemadison@INETONE.NET>
>
>Hello all,
>
>I have a physician who would like to provide I-131 ablation for his 
>patients post removal of the thyroid by surgery.  We are a private 
>practice and would rely on the local nuclear medicine clinic in the 
>hospital to order, hold, assay, etc. the I-131.  This hospital has no 
>interest in performing inpatient therapies of 300mCi so we would seek to 
>administer 33mCi or less (IAW NRC Reg Guide 8.39) and maintain the patient 
>as an outpatient.
>
>The physician is considering the possibility of multiple 33mCi outpatient 
>I-131 fractions to accomplish the ablation procedure.  Has anyone ever 
>heard of this practice or can point to a reference on the total number of 
>fractions required to obtain a radiobiologic equivalent dose of 300mCi in 
>33mCi fractions?
>
>Your feedback is appreciated.
>
>Greg Madison, MS, DABR
>Medical Physicist
>Princetion Radiation Oncology Center


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