RE: Lead and bismuth 210 and Alzheimers

["Jacobus, John (OD/ORS)" <jacobusj@ors.od.nih.gov>]

They used to blame aluminum for Alzheimer's Disease.  I bet they can find a

lot of Po-210 and Bi-210 in the lungs, liver, etc.



-- John 

John Jacobus, MS

Certified Health Physicist 

3050 Traymore Lane

Bowie, MD  20715-2024



E-mail:  jenday1@email.msn.com (H)      



-----Original Message-----

From: Jim Nelson [mailto:nelsonjima@HOTMAIL.COM]

Sent: Saturday, June 16, 2001 12:34 AM

To: Radsafe@list.vanderbilt.edu

Subject: Lead and bismuth 210 and Alzheimers





This is an interesting assocaition.





Alzheimer Disease Association Disord 2001 Apr-Jun;15(2):106-15



Environmental lead-210 and bismuth-210 accrue selectively in the brain 

proteins in Alzheimer disease and brain lipids in Parkinson disease.



Momcilovic B, Alkhatib HA, Duerre JA, Cooley M, Long WM, Harris TR, Lykken 

GI.



Institute for Medical Research and Occupational Health, Zagreb, Croatia.



We studied the occurrence of the environmental radon daughters, 210Po (alpha



particles), and 210Bi (beta particles), in the protein and lipid fractions 

of cortical gray and subcortical white matter from the frontal and temporal 

lobes of human brains of persons with Alzheimer disease (AD), persons with 

Parkinson disease (PD), smokers, or persons with no previous evidence of 

clinical neurologic disease (controls). We found a 10-fold increase in 210Po



and 210Pb radioactivity in the protein fraction from both the cortical gray 

and subcortical white matter in AD and smokers, and a similar increase in 

the lipid fraction in PD. The pathognomonic distribution of the radon 

daughters to the lipids in PD and to the proteins in AD was inferred to 

reflect the increase of local chlorine availability to which radon daughters



bound selectively.

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