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Input to EPA Guidelines for Carcinogen Risk Assessment



This was published in the Federal Register, and may be of interest to some

of the list members.  One example they cite is an example of Chemical T that

affects the thyroid, and relate it to radiation affects in Appendix D.

Sorry for the length.



-- John

John Jacobus, MS

Certified Health Physicist 

3050 Traymore Lane

Bowie, MD  20715-2024



E-mail:  jenday1@email.msn.com (H)      



[Federal Register: November 29, 2001 (Volume 66, Number 230)]

[Notices]               

[Page 59593-59594]

-----------------------------------------------------------------------



ENVIRONMENTAL PROTECTION AGENCY

 

Notice of Opportunity To Provide Additional Information and 

Comment



AGENCY: Environmental Protection Agency (EPA).



ACTION: Notice of opportunity to provide additional information and 

comment on draft revised Guidelines for Carcinogen Risk Assessment 

(July 1999), availability of draft revised Guidelines, and adoption of 

draft revised Guidelines as interim guidance.



-----------------------------------------------------------------------



SUMMARY: EPA is today announcing its intent to proceed to issue final 

revised Guidelines for Carcinogen Risk Assessment in 2002. The Agency 

is soliciting additional scientific information and comments that could 

assist us in completing the final Guidelines. In 1996, EPA published 

for public comment proposed revisions to EPA's 1986 Guidelines for 

Carcinogen Risk Assessment. Since the 1996 proposal, we have benefitted 

from extensive public comment and scientific peer review, including 

three reviews by EPA's Science Advisory Board (SAB). EPA scientists are 

currently addressing these comments under the auspices of the Agency's 

Science Policy Council. The draft revised Guidelines from which the 

Agency will proceed to make its final revisions is that provided to the 

SAB in July 1999 (with minor formatting changes). Even though EPA has 

received considerable input from the public during the 1996 public 

comment period and thereafter, we are providing an additional 

opportunity for the public to provide (1) information or comment on 

experience gained in applying the 1996 proposed Guidelines or the 1999 

draft revised Guidelines and (2) other new information or comment that 

addresses issues raised during the public comment period and the SAB 

reviews. The major issues currently being considered by EPA as it 

proceeds to issue final Guidelines are identified in the Supplementary 

Information section of this notice. Information and comments already 

submitted to EPA need not be resubmitted. Until final Guidelines are 

issued, the July 1999 draft revised Guidelines will serve as EPA's 

interim guidance to EPA risk assessors preparing cancer risk 

assessments.



DATES: Information and comments should be received by January 28, 2002.



ADDRESSES: The draft revised Guidelines for Carcinogen Risk Assessment 

are available via the Internet from www.epa.gov/ncea/raf/cancer.htm. 

Also available here are supplementary materials described within the 

Supplementary Information section of this notice. A limited number of 

paper copies of the draft revised Guidelines are available from the 

Technical Information Staff (8623D), NCEA-W, U.S. Environmental 

Protection Agency, 1200 Pennsylvania Avenue, NW., Washington, DC 20460; 

telephone: 202-564-3261; facsimile: 202-565-0050.

    You may submit information and comments in paper form or by e-mail. 

Your comments will be most useful if you include appropriate and 

detailed supporting rationale, data, and analysis. Send paper copies of 

information and comments (in duplicate if possible) to the Air Docket at the

address 

listed below. You may also submit information and comments via e-mail 

to ``a-and-r-Docket@epa.gov.'' In your correspondence, refer to Docket 

ORD-CAN-2001-01. EPA's Air Docket makes materials related to this 

notice available for review in Public Docket No. ORD-CAN-2001-01 at the 

following address: U.S. Environmental Protection Agency (EPA), Air 

Docket (6102), Room M-1500 (on the ground floor in Waterside Mall), 401 

M Street, SW., Washington, DC 20460 between 8 a.m. and 5:30 p.m., 

Monday through Friday, except on government holidays. You can reach the 

Air Docket by telephone at (202) 260-7548, and by facsimile (202) 260-

4400. We may charge a reasonable fee for copying docket materials, as 

provided in 40 CFR part 2.

    Persons providing information or comments should not submit 

personal information (such as medical data). If you submit proprietary 

information for our consideration, you should clearly separate it from 

non-proprietary information and comments by labeling it Confidential 

Business Information and send it directly to the contact person listed 

below under For Further Information instead of the public docket. This 

will help ensure that no one inadvertently places proprietary 

information in the public docket. Acknowledgments will not be sent.



FOR FURTHER INFORMATION CONTACT: Dr. William P. Wood, Risk Assessment 

Forum (mail code 8601D), U.S. Environmental Protection Agency, 

Washington, DC 20460, telephone (202) 564-3361, or send electronic mail 

inquiries to risk.forum@epa.gov.



SUPPLEMENTARY INFORMATION:

. . .

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