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Re: Mechanisms are Needed to Explain Cohen's Data



A couple of comments:

LNT is not a mechanism - it is more of a hypothesis and description of an 

extrapolation.



Mechanisms are phenomena like damage - as a result of ionizations (often 

clustered), signal transduction on a molecular level, DNA repair, expression 

of genes related to metastasis and so on. For the full tumor effect (someone 

eventually dying from it) anything from one to 8 or 10 events may be 

necessary. Therefore the LNT hypothesis needs a definition that is relevant 

to this context (number of events) - otherwise this discussion may go on for 

ever without any meaningful conclusions emerging.



The discussion would benefit from a clear distinction between observation 

and interpretation (as a few other Radsafers already pointed out with 

different wordings). We don't need a semantic excercise to understand this. 

For instance - is there any information related to socio-economic groups for 

the data discussed? (hypothesis: differences in lifestyles)



My personal ideas only,



Bjorn Cedervall     bcradsafers@hotmail.com







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