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Re: Mechanisms are Needed to Explain Cohen's Data
A couple of comments:
LNT is not a mechanism - it is more of a hypothesis and description of an
extrapolation.
Mechanisms are phenomena like damage - as a result of ionizations (often
clustered), signal transduction on a molecular level, DNA repair, expression
of genes related to metastasis and so on. For the full tumor effect (someone
eventually dying from it) anything from one to 8 or 10 events may be
necessary. Therefore the LNT hypothesis needs a definition that is relevant
to this context (number of events) - otherwise this discussion may go on for
ever without any meaningful conclusions emerging.
The discussion would benefit from a clear distinction between observation
and interpretation (as a few other Radsafers already pointed out with
different wordings). We don't need a semantic excercise to understand this.
For instance - is there any information related to socio-economic groups for
the data discussed? (hypothesis: differences in lifestyles)
My personal ideas only,
Bjorn Cedervall bcradsafers@hotmail.com
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