Re: Hormesis markers in population around NPP??

["Jerry Cohen" <jjcohen@PRODIGY.NET>]

>From what we have learned on radsafe, this study appears to be useless

because:



*all possible confounding factors were not considered.

*no mechanism established

*not endorsed by NCRP, EPA, or any authoritative body

*not published in an Epid. Journal

*no meteorological data

*Hormesis not accepted by lots of people, so it must be wrong



To save a lot of effort, they should have determined the right answer

before they did the study:-)





----- Original Message -----

From: Jim Muckerheide <jmuckerheide@cnts.wpi.edu>

To: <rad-sci-l@ans.ep.wisc.edu>

Cc: <radsafe@list.vanderbilt.edu>

Sent: Thursday, January 10, 2002 4:44 PM

Subject: Hormesis markers in population around NPP??





> Friends,

>

> FYI. Comments? Let me know if you can review the paper? Let me know if

> you don't have it.

>

> Regards, Jim

> ===========

>

> Sci Total Environ  2001 Dec 3;280(1-3):165-72

>

> Peripheral blood cells among community residents living near nuclear

> power plants.

>

> Lee YT, Sung FC, Lin RS, Hsu HC, Chien KL, Yang CY, Chen WJ.

>

> Department of Internal Medicine, National Taiwan University College of

> Medicine, Taipei, ROC.

>

> Abstract

> Information about hematopoieses as a result of exposure to very low

> levels of radiation is scarce. To investigate the human hematopoietic

> effect of very low level radiation exposure, measurements of peripheral

> blood components were performed among 3602 men and women, aged 35 and

> above, living in a community near two nuclear power installations in

> Chinshan, Taiwan. The radiation level that each individual was exposed

> to was represented by a surrogate level, '1 / D1^2  + 1 / D2^2,', a

> transformed distance from each individual's residence to the two power

> plants D1 and D2. In addition to comparing average hematology

> measurements, multiple regression analyses were done to include age,

> gender, smoking, drinking status and the surrogate radiation exposure

> level as independent variables. Univariate and bivariate analyses showed

> that the hematology measurements had significant associations with age,

> gender, smoking or drinking. The multiple regression analyses revealed

> that significant positive associations with '1 / D1^2  + 1 / D2^2,' were

> found for hemoglobin, hematocrit, platelet, white blood cell and red

> blood cell. The platelet count might increase for 208.7 x 10^3/microl if

> the exposure from the nuclear plants increased by one exposure unit.

> This type of association implies that those who lived closer to the

> nuclear power installation had a higher blood cell count; we suspect

> that this could be a type of radiation hormesis.

>

>

>

>

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