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Re: radon - documentation of exposure.../LNT, chromosomes, cancer...
I wanted to take the discussion in steps to see on which points we can
agree. As a response to the below - this just shows as I have written many
times before with different wordings that we are into a semantic
pseudodebate - because we are refering to different aspects of the cancer
process.
In addition - so that you don't understand me - I am not particularly
worried about radiation - it is about probabilities all this with what
happens to DNA. Here in Stockholm it is more likely that you die from ice
falling down from buildings, cars, junk foods, depression over dark winters
or what ever (suicide maximum is usually in March).
Bad politics may be our worst radiation hazard - people delaying the time
for offspring (due to pressed personal economy - there are studies on
this...) accumulate a lot of DNA damage to their gametes (which cause me to
associate with the political anti-recycling from the NPP industry because an
undetected undecayed atom may end up in the zipper of someone's pants). Just
do the calculation and compare with any kinds of exposure! And then we spend
billions (whatever currency) on possible risks (magnetic fields from power
lines is an example).
I cannot comment more now - I have heavy lecture duties for the next two
days.
Bjorn Cedervall bcradsafers@hotmail.com
>---------------------------------------
> Do you agree that irreversible DNA damage can occur due to ionizing
> radiation exposure?
>
> BTW: The most sensitive studies for induction of chromosomal aberrations
(micronuclei, Cs-137) show an absolutely straight line down to 2.3 mGy if I
recall correctly. The same seems to be true for point mutations in somatic
cells with increasing age.
------
--Isn't it obvious that any effect which is directly caused by
radiation, with no other complications that can depend on radiation, must
follow LNT, at least if there is no more than one hit per cell
involved? The effect of a hit on one cell cannot depend on how many hits
there are on other far away cells. Presumably this applies to chromosome
aberrations if repair processes are not applicable or are not sensitive
to radiation.
But for cancer death, there are many intervening steps that depend on
radiation -- production of repair enzymes, radiation stimulated apoptosis,
stimulation of the immune system, etc.
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