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Re: radon - documentation of exposure.../LNT, chromosomes, cancer...



I wanted to take the discussion in steps to see on which points we can 

agree. As a response to the below - this just shows as I have written many 

times before with different wordings that we are into a semantic 

pseudodebate - because we are refering to different aspects of the cancer 

process.



In addition - so that you don't understand me - I am not particularly 

worried about radiation - it is about probabilities all this with what 

happens to DNA. Here in Stockholm it is more likely that you die from ice 

falling down from buildings, cars, junk foods, depression over dark winters 

or what ever (suicide maximum is usually in March).



Bad politics may be our worst radiation hazard - people delaying the time 

for offspring (due to pressed personal economy - there are studies on 

this...) accumulate a lot of DNA damage to their gametes (which cause me to 

associate with the political anti-recycling from the NPP industry because an 

undetected undecayed atom may end up in the zipper of someone's pants). Just 

do the calculation and compare with any kinds of exposure! And then we spend 

billions (whatever currency) on possible risks (magnetic fields from power 

lines is an example).



I cannot comment more now - I have heavy lecture duties for the next two 

days.



Bjorn Cedervall   bcradsafers@hotmail.com

>---------------------------------------

 > Do you agree that irreversible DNA damage can occur due to ionizing

 > radiation exposure?

 >

 > BTW: The most sensitive studies for induction of chromosomal aberrations 

(micronuclei, Cs-137) show an absolutely straight line down to 2.3 mGy if I 

recall correctly. The same seems to be true for point mutations in somatic 

cells with increasing age.

------

	--Isn't it obvious that any effect which is directly caused by

radiation, with no other complications that can depend on radiation, must 

follow LNT, at least if there is no more than one hit per cell

involved? The effect of a hit on one cell cannot depend on how many hits

there are on other far away cells. Presumably this applies to chromosome

aberrations if repair processes are not applicable or are not sensitive

to radiation.

	But for cancer death, there are many intervening steps that depend on 

radiation -- production of repair enzymes, radiation stimulated apoptosis, 

stimulation of the immune system, etc.







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