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RE: Cancer deficiency clusters



Howard,

But if we question the validity of statistical cluster that show a higher

increase of cancer near a power plant, it should be, and is, statistically

probable that studies will show a statistical cluster of healthful effects

of radiation.



You noted the Nuclear Shipyard Worker Study.  It you like, I will send a

copy of the abstract written by one of the authors of the study, Dr.

Genevieve Matanoski.  It appeared in Radiation Research 133, 126-127 (1993).

(I think it is important to supply references rather than speculations,

don't you?)  Quoting the abstract:



"The data clearly indicate that both nuclear worker groups have a lower

mortality from leukemia and lymphatic and hematopoietic cancers than does

the nonnuclear group.  All three groups have lower rates than the general

population.  However, if the NW<5.0 or the 5.0-9.0 mSv group is used for

comparison, than all dose groups 10 mSv and above in the NW>/= 5.0 group

have higher mortality rates that the NW<5.0 group for both leukemia and all

lymphatic hematopoietic neoplasms.  There is no consistent dose response

with radiation, which would suggest that radiation is not the factor

associated with the increase. . . . The SMRs are very sensitive to any

changes, such as lagging, due to small numbers, so these within-group

observations may simply represent chance variations."



A couple of simplistic observations, since I am not an epidemiologist but

feel that I can understand the basics.  First, this is a cohort study, which

may not have any relevance to public exposures.  I guess that if you want to

reduce your risk of cancer, you should work in Naval shipyard, since "All

three groups have lower rates than the general population."  Second, the

risk mortality increases at occupational exposures above 10 mSv.    Third,

other factors that were not considered, such as asbestos exposures, may

influence the results as they may be more important than the factor,

radiation, that is being studied.  For example, the study indicates that the

mortality from lung cancer for all groups was higher than that of the

general population.  But only the non-nuclear workers had a statistically

significant increase.  I guess you can conclude that radiation reduces the

risk of lung cancer in this cohort.  Of course, I would rather a more

qualified epidemiologist than I review the data.  While I admire John

Cameron for his work, he is not an epidemiologist either.



-- John 

John Jacobus, MS

Certified Health Physicist 

3050 Traymore Lane

Bowie, MD  20715-2024



E-mail:  jenday1@email.msn.com (H)      



-----Original Message-----

From: hflong@postoffice.pacbell.net

[mailto:hflong@postoffice.pacbell.net]

Sent: Friday, July 19, 2002 7:03 AM

To: jjcohen

Cc: Gibbs, S Julian; Jacobus, John (OD/ORS); Radsafe Mail list

Subject: Re: Cancer deficiency clusters





Yes, Jerry,

Such a study has been done on 27,872 nuclear shipyard workers - but until

recently only reported as not showing expected increase in cancer.



John Cameron, one of 8 members of the technical advisory committee of the

Nuclear Shipyard Workers Study reports, "The cancer death rate of the NW>0.5

group [those receiving an extra 0.5 rem] was over 4 std.dev. lower than the

NNW control group [non-nuclear workers of similar ages and jobs]. This good

news is not mentioned but the data are available in the final report."

http://www.aps.org/units/fps/oct01/a5oct01.html

. . .

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