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Re: I-131 Tx to pregnant patient



Please, GO TO http://www.icrp.org/educational_area.asp



LOOK AT ICRP 84, PREGNANCY AND MEDICAL RADIATION, download and



GO TO NUCLEAR MEDICINE AND PRAGNANT PATIENTS



LOOK AT THE TABLE - Approximate whole body fetal dose (mGy) from common

nuclear medicine procedures







and you will find your answer







Jose Julio Rozental



joseroze@netvision.net.il



Israel















----- Original Message -----

From: <JGarrett@mbhs.org>

To: <radsafe@list.vanderbilt.edu>

Sent: Monday, December 22, 2003 11:59 PM

Subject: I-131 Tx to pregnant patient





> Dear Rad Safers:

>

> I was just informed that there was a patient a couple of weeks ago who

> received an I-131 treatment for residual thyroid disease post

> thyroidectomy. The pregnancy test on the day of the therapy was negative.

> However, a few days later, 5 -6, the patient's period was late. The

> subsequent serum test demonstrated a positive test for pregnancy. I have

> done some initial calculation for the dose to the uterus/embryo. The

amount

> of I-131 administered was 75 mCi. The calculations I have performed are

> given below. My first question is what method would yall use since there

is

> such a drastic difference between the two methods? Thanks for your help.

>

> NRC Guide 8.36 Radiation Dose to the Embryo/Fetus Method

> Dose = I x f1 x DF, where I = initial activity in uCi = 75 mCi=75000 uCi,

> f1 is fractional uptake to the blood = 1.00, and DF is the dose factor =

> 3.64E-3 rem/uCi

> Dose = (75000 uCi)*(1.00)*(3.64E-03 rem/uCi) = 273 rem => 273 rads to the

> embryo.

>

> Using Tabular values from internaldosimetry.com

> Dose to Uterus = 2.2E-01 rad/mCi

> Dose = (75 mCi)*(2.2E-01 rad/mCi) = 16.5 rad to the embryo

>

>

> Jeffrey A. Garrett, MS, DABR

> Chief Physicist

> Mississippi Baptist Medical Center

> 1225 North State Street

> Jackson, MS 39202

>

> Office: 601-968-1725

> Cancer Center: 601-968-1416 or 1420

> Fax: 601-960-3317

>

>

>

>

>

> The information contained in this email is confidential and is intended

for the recipient only.  Do not forward this email without permission from

its originator.

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