Re: Radiation Hormesis

[Kai Kaletsch <eic@shaw.ca>]

John Flood wrote: "Given the low dose levels at which hormesis may exist, it

seems to me that a definitive study to prove or disprove the theory would

require test and control populations that should be impossibly large"



Low dose does not mean small effect. (no one is claiming LNT for hormesis).

The size of the population that you need for a study is dependent on the

size of the expected result (the dependent variable), not on the amount of

extra dose (the independent variable).



Kai



----- Original Message ----- 

From: "Flood, John" <FloodJR@NV.DOE.GOV>

To: "'jjcohen'" <jjcohen@PRODIGY.NET>; "Franz Schoenhofer"

<franz.schoenhofer@CHELLO.AT>; <RuthWeiner@AOL.COM>; ""Joan Stovall""

<joans@PCEZ.COM>; ""Karl Ellison"" <ellison1@localnet.com>;

<radsafe-digest@list.vanderbilt.edu>

Sent: Tuesday, January 20, 2004 5:19 PM

Subject: RE: Radiation Hormesis





> I had the good fortune of hearing Dr. Lucky speak on this subject - most

> entertaining, in addition to being informative - he made his case very

well.

> Given the low dose levels at which hormesis may exist, it seems to me that

a

> definitive study to prove or disprove the theory would require test and

> control populations that should be impossibly large, and thus the study

can

> never be done.  That would mean that hormesis is destined to remain no

more

> than a theory.  Do others concur on this?  Or might there be a way to test

> for and prove/disprove hormesis in humans?

>

> Bob Flood

> NTS Dosimetry

>

>

> -----Original Message-----

> From: jjcohen [mailto:jjcohen@PRODIGY.NET]

> Sent: Tuesday, January 20, 2004 2:57 PM

> To: Franz Schoenhofer; RuthWeiner@AOL.COM; "Joan Stovall"; "Karl Ellison";

> radsafe-digest@list.Vanderbilt.Edu

> Subject: Re: Radiation Hormesis

>

>     In following this string on "radiation hormesis" it occurs to me that

> there must be some radsafers who are reasonably familiar with the

scientific

> evidence supporting hormesis, but are unconvinced that it is a valid

> phenomenon.

>     Just out of curiosity, I wonder what kind, or quality of evidence

would

> it take to convince you that hormesis is for real and ought to be taken

> seriously in formulating radiation policies? Would anyone care to take a

> crack at that?

>

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