RE: Hormetic Effects of Radiation should not be limited to cancer

[John Jacobus <crispy_bird@YAHOO.COM>]

I continue to believe that there are really two issue

or types of studies.  Cellular research will help to

determine the mechanism of radiation effects.  This

involves the study of DNA repair, bystander effects,

etc., and is science



The second issue is using radiological studies to

ensure the safety of workers and the public.  In this

case, epidemiological studies should be used. The LNT

is based on epidemiological studies and is a

REGULATORY tool.  However, the limits are not clearly

stated, which makes it dogma.



--- andre geerdink <volkswagen181@HOTMAIL.COM> wrote:



> I agrea you are right about cells behaving in a more

> simple fashion than a 

> complete organism.

> I think in research for the mechanisms behind any

> biology, this is exactly 

> the reason to test different hyoptesis on

> cellcultures and on DNA level 

> first. Complete organisms are too complex.

> If you know about the basic reactions of different

> types of cells, only then 

> you can design clever  experiments on organisms and

> test the right factors 

> in epidemiological studies.

> 

> André Geerdink

> 

> 

> 

> >From: "Stabin, Michael"

> <michael.g.stabin@vanderbilt.edu>

> >Reply-To: "Stabin, Michael"

> <michael.g.stabin@vanderbilt.edu>

> >To: <RuthWeiner@AOL.COM>,

> <jrcamero@wiscmail.wisc.edu>,        

> ><goldinem@SONGS.SCE.COM>

> >CC: <radsafe@list.vanderbilt.edu>

> >Subject: RE: Hormetic Effects of Radiation should

> not be limited to cancer

> >Date: Fri, 10 Sep 2004 18:15:30 -0500

> >

> > >The persistence of the LNT is not due to

> ignorance about how the body

> >functions, but to the large regulatory investment

> in that theory.

> >Moreover, people (even scientists!) are often

> unwilling to see the

> >evidence that destroys their pet theories.

> >

> >I agree, even while I don't believe in ICRP

> "conspiracy theories". The

> >problem is that we have some evidence in certain

> studies, mostly at the

> >cellular level, that indicate some isolated effects

> that are clearly

> >demonstrable, but difficult to relate to the

> organism level. The same

> >holds for the bystander effect, whose evidentiary

> basis is also strong,

> >but which (on its face) contradicts evidence from

> valid experiments

> >seeming to show a hormetic response. Because we see

> "changes in cells"

> >from either does not indicate clearly how the

> organism, with its

> >complexities of damage, repair, and cellular

> reproduction cycles, will

> >ultimately respond. Then we have epidemiological

> studies, often with

> >poor bases, from which people derive conclusions

> that suit them. I

> >believe that if folks could get off their political

> agendas for a while

> >and look at the biological evidence in toto, we

> could find some answers

> >that would explain all of these effects and point

> us towards the

> >correct, rational, dare I say scientific, policy

> for the future.

> >

> >

> >Mike

> >

> >Michael G. Stabin, PhD, CHP

> >Assistant Professor of Radiology and Radiological

> Sciences

> >Department of Radiology and Radiological Sciences

> >Vanderbilt University

> >1161 21st Avenue South

> >Nashville, TN 37232-2675

> >Phone (615) 343-0068

> >Fax   (615) 322-3764

> >Pager (615) 835-5153

> >e-mail     michael.g.stabin@vanderbilt.edu

> >internet   www.doseinfo-radar.com

> >

> >

> >

> 

>

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> 





=====

+++++++++++++++++++

"A devotee of Truth may not do anything in deference to convention.  He must always hold himself open to correction, and whenever he discovers himself to be wrong he must confess it at all costs and atone for it."

Monhandas K. Gandhi, in "Autobiography"



-- John

John Jacobus, MS

Certified Health Physicist

e-mail:  crispy_bird@yahoo.com





		

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