Re: European Residential Radon Pooling

[niton@mchsi.com]

Ruth,



The overall risk findings of the two methods rarely produce identical results, 

but are often similar.  As Harvey Checkoway points out - Summarizing 

epidemiologic data from multiple studies can be accomplished either by a meta-

analysis of published findings or by pooling data and performing new analyses 

of enlarged data sets. Meta-analysis is relatively easy and inexpensive to 

perform but usually is restricted to examination of overall risks. Data pooling 

offers a more direct approach for subcohort analyses and for estimation of dose-

response relationships. The advantages of pooling data from multiple studies 

with similar exposures pertain primarily to enlarged study bases and a greater 

potential for evaluating statistically stable dose-response relationships than 

can be accomplished by meta-analysis. 

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