[ RadSafe ] N. American Residential Lung Cancer Study

[niton at mchsi.com]

Dr. Seiler,

The information you requested is in Table 5.  It clearly shows a statistically 
sigificant excess odds ratio at 100 Bq/m3 for homes monitored over 10 years.  
As pointed out in the paper, "Field et al. have recently demonstrated that 
empiric models with improved retrospective radon exposure estimates were more 
likely to detect an association between prolonged residential radon
exposure and lung cancer."   

http://www.aarst.org/news_pdf/2002_IowaU_Follow-up_Study.pdf


Further, "Odds ratios exhibit no apparent evidence of nonlinearity
throughout the range of radon concentrations observed
in these studies."

If you or Dr. ALvarez have any concerns about the analysis or its 
inperpretation, we would welcome a letter-to-the-editor regarding your 
concerns.  

Regards, Bill

R. William Field, M.S, Ph.D.
Associate Professor
College of Public Health
Department of Occupational and Environmental Health
University of Iowa
Iowa City, IA 52242

319-335-4413
bill-field at uiowa.edu


> Hi All,
> 
> I am just working in this area with Joe Alvarez, so I have a 
> simple question:
> Where are these analyses that show a clear-cut dose-response 
> relationship even below the EPA action levels? Or to put it 
> more bluntly:
> 
> We hear you, so WHERE IS THE BEEF?
> 
> Best regards,
> 
> Fritz
> 
> 
> *****************************************************
> Fritz A. Seiler, Ph.D.
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> 
> 
> -----Original Message-----
> From: radsafe-bounces at radlab.nl [mailto:radsafe-bounces at radlab.nl] On
> Behalf Of niton at mchsi.com
> Sent: Tuesday, March 08, 2005 1:30 AM
> To: Otto G. Raabe
> Cc: RadSafe
> Subject: Re: [ RadSafe ] Residential Lung Cancer Study
> 
> 
> There is a clear statistically significant dose-response relationship
> (even 
> below the EPA's action level) as better measures of retrospective radon
> gas 
> estimates are used. Even the analyses using data from homes that
> included 
> measurements of radon reflecting a limited percent of the exposure
> period nealy 
> produced a statistically significant dose response.
> 
> 
>