Re[2]: Thyroidectomy/Thyroid Burden Measurements -Forwarded

[michael_coogen@ccgw1.hq.dla.mil]

     We as individuals are unique unto ourselves.  We are genetically 
     different.  I'm not familar with Mike's 6 hour clearance half life but 
     you must take into account the following:
     
        Different metabolic rate
        Post Thyroidectomy
        Age of Patient
        Resposnse to the radiopharmaceutical
     
     You can give 10 patients Iodine-131 and in most cases you will have 
     different metabolic responses, depending upon how much of residual 
     thyroid gland was left behind.  Surgeons remove as much as they can 
     and that depends upon the etiology and condition of the patient.  Each 
     patient is different and each patient will respond different.  In fact 
     if you increase the therpay to a larger population you will see the 
     deviations more statistical....Cannot rationalize or conclude anything 
     from one patient..You must accept it for what it is...mike coogen


______________________________ Reply Separator _________________________________
Subject: Re: Thyroidectomy/Thyroid Burden Measurements -Forwarded -Re
Author:  radsafe@romulus.ehs.uiuc.edu at ~GW1
Date:    2/22/96 10:16 AM


We monitor I-131 therapy patients given 100-200 mCi to determine when 
they drop below the 30 mCi outpatient limit.  In our crude way
of doing things we usually see an apparent 24 hr clearance half life. 
Younger/healthier patients may be quite a bit faster than this, but 
some patients are longer.  Given that our technique of measuring
dose rate at 1 meter is crude, how do we explain our observations 
given Mike's 6 hour clearance half-life?
     
Dale Boyce
dale@radpro.uchicago.edu