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Re[2]: Potassium Iodide administration



     I agree with Chris Alston's comments.  Potassium Iodide is potentially 
     extremely cardio-toxic and should not be used indiscriminately.  
     Rather than a physician, I would recommend interacting with either a 
     pharmacologist or toxicologist.  They have more experience in these 
     matters.  Nevertheless, it seems that engineering controls are more in 
     order than potentially increasing personnel risk.
     
     Lorraine Day, PhD
     RSO CAMD Project
     LSU
     day@camd.lsu.edu


______________________________ Reply Separator _________________________________
Subject: Re: Potassium Iodide administration
Author:  radsafe@romulus.ehs.uiuc.edu at Internet
Date:    4/29/97 11:04 AM


This sounds very ill-advised, to me. If the investigators are receiving 
significant intakes of radioiodine, procedural, or engineering, changes 
should be made to control/reduce them. Physiologic changes could result from 
the long-term, routine, consumption of stable iodine, at quantities greatly 
in excess of those required by the normal metabolism (150 ug/day). That is 
what would be required to reduce their uptake. Large quantities of stable 
iodine (>100mg) are given, to BLOCK the thyroid, when an acute intake that 
may result in deterministic effects, or greatly increase the risk of 
stochastic effects, has occurred (or is likely to occur). Where are they, 
relative to your ALARA levels, and why?
     
chris alston
ccja@aol.com