[ RadSafe ] Fwd: (Correction) Are rodents good models for studing radiaton-induced cancers?
crispy_bird at yahoo.com
Wed Aug 9 15:13:20 CDT 2006
Apparently, I did not supply the correct link to the
article itself. It is at
Sorry for the confusion.
--- John Jacobus <crispy_bird at yahoo.com> wrote:
> Date: Wed, 9 Aug 2006 13:07:21 -0700 (PDT)
> From: John Jacobus <crispy_bird at yahoo.com>
> Subject: Are rodents good models for studing
> radiaton-induced cancers?
> To: radsafe <radsafe at radlab.nl>,
> know_nukes at yahoogroups.com
> I saw this article and thought that it raises some
> intriguing questions.
> Nature Reviews Cancer 5, 807-819 (2005)/nrc1715
> CANCER IN RODENTS: DOES IT TELL US ABOUT CANCER IN
> Vladimir N. Anisimov, Svetlana V. Ukraintseva &
> Anatoly I. Yashin
> Information obtained from animal models (mostly mice
> and rats) has contributed substantially to the
> development of treatments for human cancers.
> important interspecies differences have to be taken
> into account when considering the mechanisms of
> development and extrapolating the results from mice
> humans. Comparative studies of cancer in humans and
> animal models mostly focus on genetic factors. This
> review discusses the bio-epidemiological aspects of
> cancer manifestation in humans and rodents that have
> been underrepresented in the literature.
. . .
>From an article about physicians doing clinical studies:
"It was just before an early morning meeting, and I was really trying to get to the bagels, but I couldn't help overhearing a conversation between one of my statistical colleagues and a surgeon.
Statistician: "Oh, so you have already calculated the P value?"
Surgeon: "Yes, I used multinomial logistic regression."
Statistician: "Really? How did you come up with that?"
Surgeon: "Well, I tried each analysis on the SPSS drop-down menus, and that was the one that gave the smallest P value"."
John Jacobus, MS
Certified Health Physicist
e-mail: crispy_bird at yahoo.com
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