[ RadSafe ] Fwd: (Correction) Are rodents good models for studing radiaton-induced cancers?

[John Jacobus]

Apparently, I did not supply the correct link to the
article itself.  It is at 
http://www.nature.com/nrc/journal/v5/n10/full/nrc1715_fs.html

Sorry for the confusion.

--- John Jacobus <crispy_bird at yahoo.com> wrote:

> Date: Wed, 9 Aug 2006 13:07:21 -0700 (PDT)
> From: John Jacobus <crispy_bird at yahoo.com>
> Subject: Are rodents good models for studing
> radiaton-induced cancers?
> To: radsafe <radsafe at radlab.nl>,
> know_nukes at yahoogroups.com
> 
> I saw this article and thought that it raises some
> intriguing questions.
> -------------------
> Nature Reviews Cancer 5, 807-819 (2005)/nrc1715 
>   
> CANCER IN RODENTS: DOES IT TELL US ABOUT CANCER IN
> HUMANS?  
> 
> Vladimir N. Anisimov, Svetlana V. Ukraintseva &
> Anatoly I. Yashin
> 
> Abstract
> 
> Information obtained from animal models (mostly mice
> and rats) has contributed substantially to the
> development of treatments for human cancers.
> However,
> important interspecies differences have to be taken
> into account when considering the mechanisms of
> cancer
> development and extrapolating the results from mice
> to
> humans. Comparative studies of cancer in humans and
> animal models mostly focus on genetic factors. This
> review discusses the bio-epidemiological aspects of
> cancer manifestation in humans and rodents that have
> been underrepresented in the literature.
> 
> Summary
> 
. . .

+++++++++++++++++++
>From an article about physicians doing clinical studies: 

"It was just before an early morning meeting, and I was really trying to get to the bagels, but I couldn't help overhearing a conversation between one of my statistical colleagues and a surgeon.

Statistician: "Oh, so you have already calculated the P value?"

Surgeon: "Yes, I used multinomial logistic regression."

Statistician: "Really? How did you come up with that?"

Surgeon: "Well, I tried each analysis on the SPSS drop-down menus, and that was the one that gave the smallest P value"."

-- John
John Jacobus, MS
Certified Health Physicist
e-mail:  crispy_bird at yahoo.com

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