[ RadSafe ] " Reassembly of shattered chromosomes in Deinococcus radiodurans "
Franta, Jaroslav
frantaj at aecl.ca
Fri Oct 6 10:17:42 CDT 2006
Reassembly of shattered chromosomes in Deinococcus radiodurans
Deinococcus radiodurans is able to withstand high doses of radiation,
despite the DNA damage caused.
Genome fragments with regions of complementary sequence meet and initiate
synthesis by a DNA polymerase
to form long single-stranded ends on the fragments. The complementary
single-strand tails then pair
and regenerate long double-stranded DNA molecules that are processed into
the original circular genome.
Ksenija Zahradka et al.
10.1038/nature05160
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eaRA0Souwq0HjB0BClI0Eu
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eaRA0Souwq0HjB0BClJ0Ev
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