AW: [ RadSafe ] Permanent radioactive implants for treatment of breastcancer

[John Jacobus]

Franz,

Both I-125 and Pd-103 implant seeds are about same
size.  See
http://www.cancer-radiation.com/about/prostatebrachy.htm

The reason that so many (70) have to be implanted is
that one wants to irradiate the tumor volume to the
same therapeutic dose.  In prostate therapy, I have
heard that up to 130 I-125 seeds have been implanted.
I would expect more if necessary.  See the x-ray at
the bottom of the link above.

Both I-125 and Pd-103 are encapsuled in non-reactive
titanium seeds, and are sterilized prior to
implantation.  You do not implant Pd into the body
directly, as it might dissolve and not stay in the
injected site.  As noted at
http://www.theraseed.com/library/clinical/study7.htm
there have not been any effects associated with seed
implants

--- Franz Schönhofer <franz.schoenhofer at chello.at>
wrote:

> Sandra,
> 
> Thank you for the link, I am always eager to learn.
> 
> However this link provokes questions. Being a
> non-native speaker I have
> problems with the expression "stranded seeds". 70
> seeds seems to be a rather
> large number. Of course Pd is an extremely inert
> metal, but were the seeds
> metallic Pd? Since foreign objects (bullets, grenade
> fragments, metallic and
> other particles) are usually removed from the body
> to prevent negative
> impact I wonder how the long term behaviour of the
> seeds will be. 
> 
> >From the article it seems that this was an
> experimental approach. Has it
> been contionued and used for a large number of
> patients?
> 
> Best regards,
> 
> Franz
> 
> 
> Franz Schoenhofer, PhD
> MinRat i.R.
> Habicherg. 31/7
> A-1160 Wien/Vienna
> AUSTRIA
> 
> 
> -----Ursprüngliche Nachricht-----
> Von: radsafe-bounces at radlab.nl
> [mailto:radsafe-bounces at radlab.nl] Im Auftrag
> von Sandra Gabriel
> Gesendet: Donnerstag, 23. August 2007 18:36
> An: radsafe at radlab.nl
> Betreff: [ RadSafe ] Permanent radioactive implants
> for treatment of
> breastcancer
> 
> Information about a clinical trial using Pd-103
> permanent seed implants
> for treatment of breast cancer is available at:
> 
>
http://www.oncolink.org/resources/article.cfm?c=3&s=8&ss=23&id=12719&month=0
> 1&year=2006
>

+++++++++++++++++++
"If you guard your toothbrushes and diamonds with equal zeal, you'll probably lose fewer toothbrushes and more diamonds."
- Former national security advised McGeorge Bundy
-- John
John Jacobus, MS
Certified Health Physicist
e-mail:  crispy_bird at yahoo.com


       
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