[ RadSafe ] New cancer weapon: nuclear nanocapsules

[John Jacobus]

Jaro,
My impression is that BNCT is still experimental in
any country (two?)that is using it. I doubt if any
country is using it widely.  If it is found to be an
effective treatment, the developer could certianly
apply for FDA approval.  

Currently, there are a number of research institutes
looking at alpha particles labeled to monoclonal
antibody.  The use of monocolonal antibodies have
shown promise are being used today. 
http://www.cancer.org/docroot/ETO/content/ETO_1_4X_Monoclonal_Antibody_Therapy_Passive_Immunotherapy.asp

Of note, Zevalin and Bexxar use radionuclides.

--- Jaro <jaro-10kbq at sympatico.ca> wrote:

> Thanks very much for posting the link to the
> article.
> Very interesting research.
> 
> But I notice an obvious error in the article :
> <quote>
> Astatine, like radium and uranium, emits alpha
> particles via radioactive
> decay. Alpha particles, which contain two protons
> and two neutrons, are the
> most massive particles emitted as radiation.
> <end quote>
> 
> In Boron-Neutron Capture Therapy (BNCT), the
> radiation emitted in the
> induced Boron fission is an alpha particle (He4
> nucleus) and a Lithium ion
> (Li7).
> Since Li7 is nearly double the mass of He4, it is
> *untrue* that "Alpha
> particles... are the most massive particles emitted
> as radiation."
> 
> Also,
> <quote>
> "There are no FDA-approved cancer therapies that
> employ alpha-particle
> radiation," said lead researcher Lon Wilson,
> professor of chemistry.
> "Approved therapies that use beta particles are not
> well-suited for treating
> cancer at the single-cell level because it takes
> thousands of beta particles
> to kill a lone cell. By contrast, cancer cells can
> be destroyed with just
> one direct hit from an alpha particle on a cell
> nucleus."
> <end quote>
> 
> This is unfortunately true, but it is simply stating
> that the US FDA hasn't
> approved BNCT.
> The way things are going, the US may be the last
> country in the world to
> approve BNCT -- right after Outer Mongolia.
> 
>  Jaro
> ^^^^^^^^^^^^^^^^^^^^^
> 
> 
> 
> -----Original Message-----
> From: radsafe-bounces at radlab.nl
> [mailto:radsafe-bounces at radlab.nl]On
> Behalf Of parthasarathy k s
> Sent: Friday, August 24, 2007 5:38 AM
> To: radsafe at radlab.nl
> Subject: [ RadSafe ] New cancer weapon: nuclear
> nanocapsules
> 
> 
> Friends,
> 
> The following news just released may be of interest
> to some of you
> 
>
http://www.eurekalert.org/pub_releases/2007-08/ru-ncw082307.php
> 
> Regards
> K.S.Parthasarathy


+++++++++++++++++++
"If you guard your toothbrushes and diamonds with equal zeal, you'll probably lose fewer toothbrushes and more diamonds."
- Former national security advised McGeorge Bundy
-- John
John Jacobus, MS
Certified Health Physicist
e-mail:  crispy_bird at yahoo.com


       
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