AW: [ RadSafe ] Drug that may prevent radiation injury

[John Jacobus]

Jim.
  And when would you apply this LDR?  If you know a radiological bomb has gone off, isn't it too late?  How much would you administer the dose and how much?  How would your arrange to give this prophylactic doses to large numbers of people?  
   
  Questions. Questions. Questions.

Jim Muckerheide <rad_sci_health at comcast.net> wrote:
  Rainer, and friends,

Re your 1) - DARPA doesn't fund "bogus science" but it does do a lot of
prelim testing of "potential" results/effects, which it terminates pretty
quickly if it doesn't show some confirmation.

Re your 2) - This report implies that this is external radiation, but do we
know for sure? Could this be internal exposure (dirty bomb or fallout)?

Note also that, where the report says:

"mice showed enhanced protection when exposed to lethal doses of ionizing
radiation when they were given [first-generation NTH drugs] prior to
exposure."

We could also quite accurately say:

"mice showed enhanced protection when exposed to lethal doses of ionizing
radiation when they were given [low dose radiation (LDR)] prior to
exposure."

LDR does have a preventive effect with exposure post-irradiation.
Biological responses are ("may be") the sequelae of the initial nanosecond
radicals and cascade. But the biology can be directly affected minutes to
hours after the initial high-dose exposure.

Best wishes.
Regards, Jim
==============

on 1/29/08 10:28 AM, Rainer.Facius at dlr.de at Rainer.Facius at dlr.de wrote:

> 1) DARPA is not known for funding bogus science.
> 
> 2) The crux indeed is whether the antioxidant, radical scavenging activity
> will help in a post-exposure scenario, i.e., when most or all of the initial
> radicals are gone long ago.
> 
> Dr. Rainer Facius
> German Aerospace Center
> Institute of Aerospace Medicine
> Linder Hoehe
> 51147 Koeln
> GERMANY
> Voice: +49 2203 601 3147 or 3150
> FAX: +49 2203 61970
> 
> -----Ursprüngliche Nachricht-----
> Von: radsafe-bounces at radlab.nl [mailto:radsafe-bounces at radlab.nl] Im Auftrag
> von Michael McCarty
> Gesendet: Dienstag, 29. Januar 2008 15:10
> An: radsafe at radlab.nl
> Betreff: [ RadSafe ] Drug that may prevent radiation injury
> 
> For your enlightenment, entertainment, and any discussion that occur:
> 
> http://www.media.rice.edu/media/NewsBot.asp?MODE=VIEW&ID=10512
> 
> Feds fund study of drug that may prevent radiation injury Defense department
> funds study of nanotube-based drug made at Rice
> 
> 

+++++++++++++++++++
"If history teaches any lesson it is that no nation has an inherent right to greatness.  Greatness has to be earned and continually re-earned."
- Norman Augustine, Chairman of the National Academies Committee 

-- John
John Jacobus, MS
Certified Health Physicist
e-mail:  crispy_bird at yahoo.com
       
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