AW: [ RadSafe ] Drug that may prevent radiation injury

[Jim Muckerheide]

Rainer, and friends,

Re your 1) - DARPA doesn't fund "bogus science" but it does do a lot of
prelim testing of "potential" results/effects, which it terminates pretty
quickly if it doesn't show some confirmation.

Re your 2) - This report implies that this is external radiation, but do we
know for sure?  Could this be internal exposure (dirty bomb or fallout)?

Note also that, where the report says:

"mice showed enhanced protection when exposed to lethal doses of ionizing
radiation when they were given [first-generation NTH drugs] prior to
exposure."

We could also quite accurately say:

"mice showed enhanced protection when exposed to lethal doses of ionizing
radiation when they were given [low dose radiation (LDR)] prior to
exposure."

LDR does have a preventive effect with exposure post-irradiation.
Biological responses are ("may be") the sequelae of the initial nanosecond
radicals and cascade.  But the biology can be directly affected minutes to
hours after the initial high-dose exposure.

Best wishes.
Regards, Jim
==============

on 1/29/08 10:28 AM, Rainer.Facius at dlr.de at Rainer.Facius at dlr.de wrote:

> 1) DARPA is not known for funding bogus science.
> 
> 2) The crux indeed is whether the antioxidant, radical scavenging activity
> will help in a post-exposure scenario, i.e., when most or all of the initial
> radicals are gone long ago.
> 
> Dr. Rainer Facius
> German Aerospace Center
> Institute of Aerospace Medicine
> Linder Hoehe
> 51147 Koeln
> GERMANY
> Voice: +49 2203 601 3147 or 3150
> FAX:   +49 2203 61970
> 
> -----Ursprüngliche Nachricht-----
> Von: radsafe-bounces at radlab.nl [mailto:radsafe-bounces at radlab.nl] Im Auftrag
> von Michael McCarty
> Gesendet: Dienstag, 29. Januar 2008 15:10
> An: radsafe at radlab.nl
> Betreff: [ RadSafe ] Drug that may prevent radiation injury
> 
> For your enlightenment, entertainment, and any discussion that occur:
> 
> http://www.media.rice.edu/media/NewsBot.asp?MODE=VIEW&ID=10512
> 
> Feds fund study of drug that may prevent radiation injury Defense department
> funds study of nanotube-based drug made at Rice
> 
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