[ RadSafe ] 'How Low Doses Of Radiation Can Cause Heart Disease And Stroke'

Monty Charles m.w.charles at bham.ac.uk
Fri Oct 23 10:57:14 CDT 2009


I don't think one can be complacent about this. Evidence is slowly mounting 
in support a low dose effect (below 0.5Gy) for non-cancer diseases. One 
factor which led ICRP (Publication 103) and UNSCEAR (2006) not to 
include non-cancer risks in their general low dose risk estimates was the 
lack of an underlying biological mechanism. The paper of Little et al is worth 
a read. Their mathematical model has a reasonable biological basis and 
predicts LNT for cardiovascular disease. The authors point out the 
limitations of the the model - but it has the great virtue of being testable by 
in-vitro, animal or human studies. It gains plausibility by predicting excess 
relative risk values in line with observed values from a range of 
epidemiology studies. The mathematics will be intractable to many but the 
table which compares model  predictions with radiation epidemiology data is 
clear. 

Monty Charles
*******************************
> Hi Mark
> 
> Thank you for sending the link to the article. It was not a new
> finding. RERF has noted it among the A-bomb 
> survivors. It appears that the effect is so small that it is
> unlikely to influence the magnitude of the currently 
> accepted risk estimates
> 
> Regards
> K S Parthasarathy
> 
> ________________________________
> From: Mark Ramsay <mark.ramsay at ionactive. co.uk>
> To: srp-uk at yahoogroups.com; Radsafe <radsafe at radlab.nl>;
> HASNET-RAD at JISCMAIL.AC.UK
> Sent: Fri, 23 October, 2009 19:19:17
> Subject: [ RadSafe ] 'How Low Doses Of Radiation Can Cause Heart
> Disease And Stroke'
> 
> Hello all.
> 
> 'How Low Doses Of Radiation Can Cause Heart Disease And Stroke'
> 
> Not 'new news' - but latest paper published today - (cat and
> pigeons
> comes to mind if this is accepted).
> 
> News article found here: http://tiny.cc/CP9Ha
> 
> Full publication of paper found here http://tiny.cc/ssgST
> 
> Regards
> 
> Mark
> 
> Mark Ramsay
> Radiation Protection Adviser
> 
> Email: mark.ramsay at ionactive. co.uk
> Web: www.ionactive.co.uk
> 
> Ionactive on Twitter
> www.twitter.com/ionactive
> 
> Ionactive Blog
> www.ionactive.co.uk/blog
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Dr Monty Charles
Reader in Radiation Physics
School of Physics & Astronomy
University of Birmingham
Edgbaston
Birmingham B15 2TT, UK
Tel +44(0)121 414 3483



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