[ RadSafe ] Cl-36 in Nuclear Medicine?

[Geo>K0FF]

I agree, Fluorine 18 is used in Pet CT. Here is a study I did on F-18, 
including urine analysis:
http://www.qsl.net/k/k0ff/Fluorine%2018%20Report/

Also Ge-68 is used to tune up the PET CT as it has a 100%  Ga-68 daughter 
with positrons.

George Dowell


----- Original Message ----- 
From: "Siegel, Barry" <siegelb at mir.wustl.edu>
To: "'Brennan, Mike (DOH)'" <Mike.Brennan at DOH.WA.GOV>; 
<radsafe at health.phys.iit.edu>
Sent: Thursday, July 15, 2010 6:12 PM
Subject: Re: [ RadSafe ] Cl-36 in Nuclear Medicine?


>I can find no evidence in the medical literature that Cl-36 has ever been 
>used for PET in humans, and I doubt it ever will be with that half life. 
>Even if only a tiny fraction of the administered activity found its way 
>into a long-lived compartment, the committed dose would be unacceptable. 
>Moreover, since PET imaging typically requires dosages in the range of 1-20 
>mCi, the disposal of RAM waste, excreta, etc. would be a significant 
>regulatory issue.  Almost everything used for imaging in medicine has a 
>half-life under a week (I-131 being a borderline exception).
>
> Barry A. Siegel, M.D.
> Division of Nuclear Medicine
> Mallinckrodt Institute of Radiology
> Washington University School of Medicine
> St. Louis, MO
>
> -----Original Message-----
> From: radsafe-bounces at health.phys.iit.edu 
> [mailto:radsafe-bounces at health.phys.iit.edu] On Behalf Of Brennan, Mike 
> (DOH)
> Sent: Thursday, July 15, 2010 4:57 PM
> To: radsafe at health.phys.iit.edu
> Subject: Re: [ RadSafe ] Cl-36 in Nuclear Medicine?
>
> I believe that Cl-36 is used as a source of positrons (Antimatter! It's
> not just for Star Trek anymore!).  Positrons are used in Positron
> Emission Tomography (PET), which uses the fact that when a positron
> encounters an electron they mutually annihilate and produce photons
> traveling in exactly opposite directions.  Using some seriously good
> detectors and some non-trivial software, the photons can be used to
> provide imaging good enough to make your brain explode (which, I
> believe, a PET scan could capture for later examination).
>
> As chlorine has a ten day biological half life, the stay time of the
> Cl-36 isn't too great (I don't know what amounts are administered).  I
> imagine that this could be hurried along by increasing salt and liquid
> intake, though as I am not a doctor, I am not prescribing potato chips
> and beer as a post-procedure regime.
>
> -----Original Message-----
> From: radsafe-bounces at health.phys.iit.edu
> [mailto:radsafe-bounces at health.phys.iit.edu] On Behalf Of
> jearadrat at aol.com
> Sent: Thursday, July 15, 2010 2:05 PM
> To: radsafe at health.phys.iit.edu
> Subject: [ RadSafe ] Cl-36 in Nuclear Medicine?
>
>
>
> Good afternoon, all:
>
> In a reqcent company training session, one of my fellow technicians
> mentioned that a nuclear medicine application was being developed for
> chlorine-36.  Considering the VERY long (3E5 yrs) half-life, what
> possible patient application can there be for this?  Or is it possible
> some erroneous information is being spread?
>
> Thanks in advance,
> John Aperans, RRPT
> Clinton, TN USA
>
>
> P.S. Please be gentle, this is my first post.
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