[ RadSafe ] CB interview on enriched U

Steven Dapra sjd at swcp.com
Wed Oct 26 21:18:06 CDT 2011

Oct. 26

         My comments follow.

Steven Dapra

At 01:50 PM 10/26/2011, you wrote:
>Mike Brennan wrote:
> >... those doing [lab work] are unaware of the existence
> > of uranium in the environment....
>Mike, are you familiar with the literature reviews on uranium or do
>you agree with Dr. Raabe and Lt. Cherry that uranium is not a
>genotoxin?  (James Salsman)

         Below, Salsman gives a link to a paper by Craft, et al. in 
the Journal of Toxicology and Environmental Health, Part B, 7:297317, 2004.

         In its section on "DNA Damage/Carcinogenicity," (p. 308), 
the authors say:

"McDiarmid et al. (2000) did not find significant differences in the 
percent of peripheral blood lymphocytes with chromosomal aberrations 
or sister chromatid exchanges (SCEs) obtained from Gulf War veterans 
who had embedded DU-containing fragments. . . .  Since DNA damage is 
dependent on both dose and duration of exposure, the absence of 
genotoxic effects may be related to variations in the parameters 
examined in this study.

Despite the lack of genotoxic effects resulting from DU exposure,. . . ."

         Apparently Craft et al. are right alongside Dr. Raabe and 
Col. Cherry in not believing that DU is a genotoxin.  Salsman has 
been tripped up by the literature he cites.

         In their Conclusions, (p. 315), Craft et al. write:

"The long-term effects of DU still have to be definitely resolved, 
and there is an obvious need for continued studies."

         Again, and in a more general form, we see the tripping up effect.


>Because the Craft et al. review --
>-- from 2004, the Hindin et al. review from 2005, and all subsequent
>reviews have agreed with the Health Physics Society figures for
>natural occurring uranium in the environment, food and tissue.


>James Salsman

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