[ RadSafe ] Chemoluminescence in Urine by pharmaceuticals

[Mike Quastel]

Urinary chemoluminescence could interfere with tritium measurements  
if you're dealing with trace levels. See the following examples:
G. ALAN ROSE  Studies on the Chemical Nature of Urinary  
Chemiluminescence. British Journal of Urology Volume 48, 61–71,1976   
<http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X. 
1976.tb02744.x/abstract>
2.	Urinary chemoluminescence is known to be present with renal and  
urinary infection, probably from neutrophils.
	<http://www.springerimages.com/Images/MedicineAndPublicHealth/ 
1-10.1007_s00467-005-1990-x-2>


3.	Urinary chemoluminescence is also elevated in smokers. <http:// 
www.ncbi.nlm.nih.gov/pubmed/7186131>

Gisler GC, Diaz J, Durán N. Electronically excited species in the  
spontaneous chemiluminescence of urine and its uses in the detection  
of pathological conditions.Physiol Chem Phys. 1982;14(4):335-42.
Regards,Mike



On Jan 11, 2012, at 8:19 PM, ROMANOWICH Larry(L) - BRUCE POWER wrote:

> Does anyone have a list of pharmaceuticals (none radioactive type)  
> that
> will cause significant chemoluminescence in an individuals urine  
> sample.
> We analyse urine samples for tritium via liquid scintillation  
> counting.
> Concern here is that if the worker is on these pharmaceuticals when
> submitting bioassay samples, it may impact the tritium result.
>
> Larry Romanowich
> Bruce Power
> 519 389 4046 ext 15556
>
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