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Re: Info on animal experiment at Los Alamos



FYI,  Gary Tietjen (rhymes with kitchen) of LANL presented a paper at the
1985 Radiation Hormesis Conf. This paper, titled "EFFECTS OF EXPOSURE TO
PLUTONIUM AND LOW-LEVEL EXTERNAL RADIATION ON LUNG CANCER RATES", concluded
with the following---- "To date, the styudies have shown that lung cancer
mortality rates among  highly exposed persons is surprisingly low, often
significantly lower than national averages".


-----Original Message-----
From: Muckerheide <muckerheide@mediaone.net>
To: Multiple recipients of list <radsafe@romulus.ehs.uiuc.edu>
Date: Tuesday, January 11, 2000 12:02 AM
Subject: Re: Info on animal experiment at Los Alamos


>Hi Philippe,
>
>Jake Spalding is a friend and supporter of our efforts.
>
>I do not find a LANL report associated with this. Prine is new to me.
>There's only one LANL library report with Prine's name, in '71, not
>related to this.
>
>I'll get Spalding's phone number in the office and forward it.
>
>Regards, Jim
>============
>
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>> Radsafers,
>>
>> At the University of Ottawa, Canada, we are examining all accessible =
>> information on the the induction of cancer in mammals, particularly at =
>> low doses and dose rates.
>> I came accross an interesting paper=20
>>
>> Authors: J.F Spalding, J.R. Prine, and G.L. Tietjen
>>
>> from Los Alamos Scientific Laboratory, University of California
>> Los alamos,
>> New Mexico
>> United states of America=20
>> (These are the affiliations given in the paper)
>>
>> Late biological effects of ionizing radiation as influenced by dose, =
>> dose rate, age at exposure and genetic sensitivity to neoplastic =
>> transformations
>>
>> published in
>>
>> Late biological effetcs of ionizing radiation, Vol II of the proceedings
=
>> of an IAEA  Conference (1978), under the reference no. IAEA-SM-224/201
>>
>> This paper reveals unconventional relationships between dose and cancer =
>> risk, but unfortanutely does not provide details on the experimental =
>> conditions such as number of animals per dose level, pathological =
>> analyses performed, incidence of specific malignancies in controls, =
>> longevity in various dose groups, etc...
>>
>> Would anyone know how I could contact one of the authors, and whether =
>> and how it would be possible to obtain detailed information on this =
>> experiment?  This information is crucial to the analysis of cancer risk =
>> at low doses and dose rates, and this experiment seems to have produced =
>> quite important information.
>>
>> Many thanks in advance!
>>
>> The information can be sent directly to me:
>>
>> Philippe Duport
>> International Centre for Low Dose Radiation Reserach
>> Institute of the Environment
>> University of Ottawa, Canada
>> Tel: (613) 562 5800,ext. 1270
>> Fax: (613) 562 5873
>> e-mail: pduport@uottawa.ca, or pduport@home.com
>>
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>> <BODY bgColor=3D#ffffff>
>> <DIV><FONT face=3DArial>Radsafers,</FONT></DIV>
>> <DIV>&nbsp;</DIV>
>> <DIV><FONT face=3DArial>At the University of Ottawa, Canada, we are =
>> examining all=20
>> accessible information on the the induction of cancer in mammals, =
>> particularly=20
>> at low doses and dose rates.</FONT></DIV>
>> <DIV><FONT face=3DArial>I came accross an interesting paper =
>> </FONT></DIV>
>> <DIV><FONT face=3DArial></FONT>&nbsp;</DIV>
>> <DIV><FONT face=3DArial>Authors: J.F Spalding, J.R. Prine, and G.L.=20
>> Tietjen</FONT></DIV>
>> <DIV>&nbsp;</DIV>
>> <DIV><FONT face=3DArial>from Los Alamos Scientific Laboratory, =
>> University of=20
>> California</FONT></DIV>
>> <DIV><FONT face=3DArial>Los alamos,</FONT></DIV>
>> <DIV><FONT face=3DArial>New Mexico</FONT></DIV>
>> <DIV><FONT face=3DArial>United states of America </FONT></DIV>
>> <DIV><FONT face=3DArial>(These are the affiliations given in=20
>> the&nbsp;paper)</FONT></DIV>
>> <DIV>&nbsp;</DIV>
>> <DIV><FONT face=3DArial>Late biological effects of ionizing radiation as
=
>>
>> influenced by dose, dose rate, age at exposure and genetic sensitivity =
>> to=20
>> neoplastic transformations</FONT></DIV>
>> <DIV>&nbsp;</DIV>
>> <DIV><FONT face=3DArial>published in</FONT></DIV>
>> <DIV>&nbsp;</DIV>
>> <DIV><FONT face=3DArial>Late biological effetcs of ionizing radiation,=20
>> </FONT><FONT face=3DArial>Vol II of the proceedings of an&nbsp;IAEA =20
>> Conference&nbsp;(1978), under the reference no. =
>> IAEA-SM-224/201</FONT></DIV>
>> <DIV><FONT face=3DArial></FONT>&nbsp;</DIV>
>> <DIV><FONT face=3DArial>This paper reveals unconventional relationships =
>> between=20
>> dose and cancer risk, but unfortanutely does not provide details on
the=20
>> experimental conditions such as number of animals per dose level, =
>> pathological=20
>> analyses performed, incidence of specific malignancies in controls, =
>> longevity in=20
>> various dose groups, etc...</FONT></DIV>
>> <DIV><FONT face=3DArial></FONT>&nbsp;</DIV>
>> <DIV><FONT face=3DArial>Would anyone know&nbsp;how I could contact one =
>> of the=20
>> authors,&nbsp;and whether and how it&nbsp;would be possible to obtain =
>> detailed=20
>> information on this experiment?&nbsp; This information is crucial to the
=
>>
>> analysis of cancer risk at low doses and dose rates, and this experiment
=
>> seems=20
>> to have produced&nbsp;quite important information.</FONT></DIV>
>> <DIV><FONT face=3DArial></FONT>&nbsp;</DIV>
>> <DIV><FONT face=3DArial>Many thanks in advance!</FONT></DIV>
>> <DIV>&nbsp;</DIV>
>> <DIV><FONT face=3DArial>The information can be sent directly to =
>> me:</FONT></DIV>
>> <DIV><FONT face=3DArial></FONT>&nbsp;</DIV>
>> <DIV><FONT face=3DArial>Philippe&nbsp;Duport</FONT></DIV>
>> <DIV><FONT face=3DArial>International Centre for Low Dose Radiation=20
>> Reserach</FONT></DIV>
>> <DIV><FONT face=3DArial>Institute of the Environment</FONT></DIV>
>> <DIV><FONT face=3DArial>University of Ottawa, Canada</FONT></DIV>
>> <DIV><FONT face=3DArial>Tel: (613) 562 5800,ext. 1270</FONT></DIV>
>> <DIV><FONT face=3DArial>Fax: (613) 562 5873</FONT></DIV>
>> <DIV><FONT face=3DArial>e-mail: <A=20
>> href=3D"mailto:pduport@uottawa.ca";>pduport@uottawa.ca</A>, or <A=20
>> href=3D"mailto:pduport@home.com";>pduport@home.com</A></FONT></DIV>
>> <DIV>&nbsp;</DIV>
>> <DIV>&nbsp;</DIV></BODY></HTML>
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