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Re: Info on animal experiment at Los Alamos
Hi Philippe,
Jake Spalding is a friend and supporter of our efforts.
I do not find a LANL report associated with this. Prine is new to me.
There's only one LANL library report with Prine's name, in '71, not
related to this.
I'll get Spalding's phone number in the office and forward it.
Regards, Jim
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> Radsafers,
>
> At the University of Ottawa, Canada, we are examining all accessible =
> information on the the induction of cancer in mammals, particularly at =
> low doses and dose rates.
> I came accross an interesting paper=20
>
> Authors: J.F Spalding, J.R. Prine, and G.L. Tietjen
>
> from Los Alamos Scientific Laboratory, University of California
> Los alamos,
> New Mexico
> United states of America=20
> (These are the affiliations given in the paper)
>
> Late biological effects of ionizing radiation as influenced by dose, =
> dose rate, age at exposure and genetic sensitivity to neoplastic =
> transformations
>
> published in
>
> Late biological effetcs of ionizing radiation, Vol II of the proceedings =
> of an IAEA Conference (1978), under the reference no. IAEA-SM-224/201
>
> This paper reveals unconventional relationships between dose and cancer =
> risk, but unfortanutely does not provide details on the experimental =
> conditions such as number of animals per dose level, pathological =
> analyses performed, incidence of specific malignancies in controls, =
> longevity in various dose groups, etc...
>
> Would anyone know how I could contact one of the authors, and whether =
> and how it would be possible to obtain detailed information on this =
> experiment? This information is crucial to the analysis of cancer risk =
> at low doses and dose rates, and this experiment seems to have produced =
> quite important information.
>
> Many thanks in advance!
>
> The information can be sent directly to me:
>
> Philippe Duport
> International Centre for Low Dose Radiation Reserach
> Institute of the Environment
> University of Ottawa, Canada
> Tel: (613) 562 5800,ext. 1270
> Fax: (613) 562 5873
> e-mail: pduport@uottawa.ca, or pduport@home.com
>
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> <BODY bgColor=3D#ffffff>
> <DIV><FONT face=3DArial>Radsafers,</FONT></DIV>
> <DIV> </DIV>
> <DIV><FONT face=3DArial>At the University of Ottawa, Canada, we are =
> examining all=20
> accessible information on the the induction of cancer in mammals, =
> particularly=20
> at low doses and dose rates.</FONT></DIV>
> <DIV><FONT face=3DArial>I came accross an interesting paper =
> </FONT></DIV>
> <DIV><FONT face=3DArial></FONT> </DIV>
> <DIV><FONT face=3DArial>Authors: J.F Spalding, J.R. Prine, and G.L.=20
> Tietjen</FONT></DIV>
> <DIV> </DIV>
> <DIV><FONT face=3DArial>from Los Alamos Scientific Laboratory, =
> University of=20
> California</FONT></DIV>
> <DIV><FONT face=3DArial>Los alamos,</FONT></DIV>
> <DIV><FONT face=3DArial>New Mexico</FONT></DIV>
> <DIV><FONT face=3DArial>United states of America </FONT></DIV>
> <DIV><FONT face=3DArial>(These are the affiliations given in=20
> the paper)</FONT></DIV>
> <DIV> </DIV>
> <DIV><FONT face=3DArial>Late biological effects of ionizing radiation as =
>
> influenced by dose, dose rate, age at exposure and genetic sensitivity =
> to=20
> neoplastic transformations</FONT></DIV>
> <DIV> </DIV>
> <DIV><FONT face=3DArial>published in</FONT></DIV>
> <DIV> </DIV>
> <DIV><FONT face=3DArial>Late biological effetcs of ionizing radiation,=20
> </FONT><FONT face=3DArial>Vol II of the proceedings of an IAEA =20
> Conference (1978), under the reference no. =
> IAEA-SM-224/201</FONT></DIV>
> <DIV><FONT face=3DArial></FONT> </DIV>
> <DIV><FONT face=3DArial>This paper reveals unconventional relationships =
> between=20
> dose and cancer risk, but unfortanutely does not provide details on the=20
> experimental conditions such as number of animals per dose level, =
> pathological=20
> analyses performed, incidence of specific malignancies in controls, =
> longevity in=20
> various dose groups, etc...</FONT></DIV>
> <DIV><FONT face=3DArial></FONT> </DIV>
> <DIV><FONT face=3DArial>Would anyone know how I could contact one =
> of the=20
> authors, and whether and how it would be possible to obtain =
> detailed=20
> information on this experiment? This information is crucial to the =
>
> analysis of cancer risk at low doses and dose rates, and this experiment =
> seems=20
> to have produced quite important information.</FONT></DIV>
> <DIV><FONT face=3DArial></FONT> </DIV>
> <DIV><FONT face=3DArial>Many thanks in advance!</FONT></DIV>
> <DIV> </DIV>
> <DIV><FONT face=3DArial>The information can be sent directly to =
> me:</FONT></DIV>
> <DIV><FONT face=3DArial></FONT> </DIV>
> <DIV><FONT face=3DArial>Philippe Duport</FONT></DIV>
> <DIV><FONT face=3DArial>International Centre for Low Dose Radiation=20
> Reserach</FONT></DIV>
> <DIV><FONT face=3DArial>Institute of the Environment</FONT></DIV>
> <DIV><FONT face=3DArial>University of Ottawa, Canada</FONT></DIV>
> <DIV><FONT face=3DArial>Tel: (613) 562 5800,ext. 1270</FONT></DIV>
> <DIV><FONT face=3DArial>Fax: (613) 562 5873</FONT></DIV>
> <DIV><FONT face=3DArial>e-mail: <A=20
> href=3D"mailto:pduport@uottawa.ca";>pduport@uottawa.ca</A>, or <A=20
> href=3D"mailto:pduport@home.com";>pduport@home.com</A></FONT></DIV>
> <DIV> </DIV>
> <DIV> </DIV></BODY></HTML>
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