The original paper.

[Jim Muckerheide <jmuckerheide@delphi.com>]

Friends,

It was noted that the immune stimulation abstract sent yesterday was not the
one I previously sent.

Sorry for the confusion.

Here it is.

>>>
Physiol Chem Phys Med NMR 1996;28(1):7-14

 Enhanced proliferation and IL-1 production of mouse splenocytes by low-dose
whole-body X-irradiation. 

 Ishii K, Hosoi Y, Ono T, Sakamoto K 
 Radiation Safety Group, Central Research Institute of Electric Power
Industry, Tokyo, Japan.

 To elucidate the stimulative effect of low-dose whole-body X-irradiation on
the immune system, in vivo, we studied its effects on some immune functions of
mouse splenocytes. 

  Results show that Concanavalin A (Con A) and phytohemagglutinin (PHA)
responses of splenocytes were significantly increased by irradiation of 2.5
cGy and 5 cGy, whereas lipopolysaccharide (LPS) response was significantly
depressed by irradiation of 5 cGy. 

  By irradiation of 2.5 cGy, Con A response was significantly accelerated at
each concentration of Con A, but the optimum concentration of Con A shifted to
a higher value of 4 micrograms/ml from 2 micrograms/ml in the control group.
When blood plasma obtained from 2.5 cGy irradiated mice was added into the
medium at 0.005-1%, the Con A response of splenocytes in another un-irradiated
mouse was significantly accelerated over that where the plasma added came from
the sham-irradiated control mice. 

  Furthermore, 2.5 cGy whole-body irradiation also enhanced the biological
activity of intracellular interleukin-1 (IL-1) of LPS-stimulated splenocytes.
>>>

Re a question on other animal health and medical treatment studies, I recently
sent a paper on LDR improved liver damage recovery.  And the life-time study
with 3 groups of 300 rats each, all in the same room: one unexposed group, and
one group exposed to 7 cGy/year, and one to 14 cGy/year (from thorium placed
under their cages). Both exposed groups lived significantly very much longer
than the unexposed group (which likely died from mid-life infections that the
enhanced radiation-exposure prevented). There are a number that prevent or
eliminate cancer by LDR. Some are presented on some the web site papers that I
linked to.

Let me know if you want the refs to these and other such confirming studies.

Regards, Jim
muckerheide@mediaone.net
Radiation, Science and Health
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