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Tc-99m Lymphoscintigraphy
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Dave Engelbretson wrote on March 16, 2000:
I was interested in learning how long medical institutions are holding
resected lymph nodes & tumor tissues before allowing pathological
examination.
What are others experiences in determining whether these tissues can be
safely examined immediately after surgical extarction ?
Dear Dave,
Tc-99m isotope, used in sentinel lymph node biopsy/dissection procedures,
offers a number of advantages over other
isotopes, low patient dose and low hospital personnel (including
pathologists) exposure among them.
We introduced this procedure in 1996 for melanoma, then for breast cancer
patients. While initially, for the first few cases,
we held the primary tumor specimens for 60 hours (conservative 10
half-lives), we found this approach too restrictive.
Not only it is not justified, such approach could potentially affect quality
of patient care as, in some cases, an immediate
preliminary histopathology evaluation is necessary. From the beginning,
there were no restrictions placed on the
excised nodes.
You can find out more about our experiences from my review paper presented
at the Midwinter HPS meeting in Anaheim, CA
in February 2001. The paper, titled "Sentinel Node Biopsy: ALARA and Other
Considerations" is printed in the "Changes in
Medical Applications" section of the proceedings titled "Radiation Safety
and ALARA Considerations for the 21st Century".
Available from: Medical Physics Publishing, 4513 Vernon Blvd, Madison, WI
53705-49964, tel: 800-442-5778 or
608-262-4021; e-mail: mpp@medicalphysics.org ($35.95).
If you need more information soon, contact me directly (e-mail is best, just
be careful with spelling my name correctly).
Jodi
Jodi Strzelczyk
Asst. Professor, Radiological Sciences
University of Colorado, HSC
Denver, CO
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