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FW: Jueneman on Radiation induced Hormesis
I got this on another listserve. I don't know how many of you saw it when
it came out in 1995. The Editor of R&D magazine apparently attended Jim
Muckerheide's ANS session on health effects of low dose radiation and got
something out of it. (Which is more than some of our friends nearer home
did :-)
And he states it very clearly.
Ted Rockwell
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Subject: Jueneman on Radiation induced Hormesis
Folks:
Find below a commentary from Frederic Jueneman of Research & Development
(R&D) Magazine on the topic of ionizing radiation induced Hormesis. Never
assume anything...
Have YOU had your Minimum Daily Requirement (MDR) of radiation today??
Paul March
Lockheed Martin Space Operations (LMSO)
2400 NASA Road 1, MS: C18
Houston, TX 77058-3799
Ph: 281-333-6854 FAX: 281-333-7620
e-mail: paul.march@LMCO.COM
INNOVATIVE NOTEBOOK
RESEARCH & DEVELOPMENT 1995
Frederic B. Jueneman, FAIC
R&D Magazine
Copyright 1995 by Frederic B. Jueneman
Late this past October I took one of my grand kids to the Open House at The
Lawrence Berkeley Laboratory complex, a Department of Energy facility
nestled high in the hills overlooking the UC Berkeley campus and devoted to
problem solving in energy, environment, health, and basic research. Included
in this array is a Genome Research Lab, one of three such labs supported by
the DOE to explore the human DNA genome through robotics and digital
microscopy. The exposition attracted students from all walks of life.
In Bldg. 2 is the historically aging Betatron, last powered up in 1993, a
relic of the Nobel laden experiments of yesteryear. But dwarfed by this
massive cyclotron was a minuscule Lexan window exhibit of a neon filled
multistage spark chamber, where cosmic rays from "somewhere out there"
zapped through every few seconds, silently ionizing the high voltage charged
neon gas with segmented orange-colored streaks, first at one angle then at
another.
The school lesson here, as a student attraction, is that such energetic
cosmic particles have been soaking the Earth for untold eons, noiselessly
bathing us in an ionizing shower that has possibly defined the radiation
threshold of our quality of life since the beginning of biological time.
By happenstance, shortly after this fascinating excursion in Berkeley I
attended the American Nuclear Society gathering across the Bay in San
Francisco where a series of international interest meetings were devoted to
low level radiation and its concomitant effects on our present quality of
life. The average person living in the US, for example, gets about 360
milli-rems radiation per year from both cosmic and terrestrial sources. The
cosmic sources are from galactic and extragalactic particles while
terrestrial origins are principally from diffusion of radon gas. Estimates
range as high as 15,000 particles per second per person.
Some curiosities were brought out at this ANS meeting that defied
explanation. Bernard L. Cohen, professor of physics at the University of
Pittsburgh, had made an independent comprehensive survey of some 1600
counties throughout the US, a study that purportedly was designed to
once-and-for-all define if not sustain the theory of linear, no-threshold
distribution on cancer-induced radiation as espoused by the Nuclear
Regulatory Commission. However, this was not what he found at all.
The standard chart on such things begins with a zero-level radiation
threshold and rises linearly toward some arbitrarily high mortality dosage.
But, up until some several hundred milli-rems there was no discernible
effect. What was shown was a slight but statistically significant decrease
in radiation-induced carcinomas at around several hundred millirems.
Furthermore, the statistical curve then dipped downward giving a negative
slope, and only returned to rise above the baseline at about 5 rems per
year, some fifty times the annual recommended limit by the NRC. Then begins
an extensive gray area where precious little is known up to about 100 rems
per year.
This finding was supported by researchers from Japan, who in the course of
their own investigations had also used the statistics supplied by the US for
Hiroshima and Nagasaki, where a study of nearly 80,000 survivors were
divided into control and exposed groups. The normalized distribution of
carcinomas showed about 120 more incidences in the unexposed group, which
ran counter to every expectation. The question is, what's going on?
The statistics for Denver and the Colorado plateau are also skewed. These
folks get an additional 90 millirems per year from both cosmic and
terrestrial sources, but have less than average incidences of cancer. This
same skewness exists for people who live in higher radon-level areas,
seemingly contrary to what we read in the mass media. Moreover, those
persons having plutonium-powered cardiac pacemakers can add 100 milli-rems
to their annual dosage.
What this seems to boil down to is what is called hormesis, a biological
term that describes the effect of a stimulating insult by a toxic substance
at nontoxic levels. Many such chemical toxins are known, such as arsenic,
copper, or selenium, which play minor but significant hermetic roles in
metabolism at relatively low concentrations.
Does this mean that radiation also is a necessary "nutrient" in the
metabolic broth, that there's a minimum daily requirement?
I would wager that it does. For one thing, Homosapiens has proliferated and
thrived for mega years in this milieu. For another, mankind has extended its
individual life span substantially over the last few centuries, due to
better living conditions, increased nutrition, and more effective medical
and sanitary practices. Humankind now encounters otherwise rare physical
insults and diseases because we live long enough to experience them.
In like manner, radiation exposure at elevated levels of up to 100 rems (per
year) is probably only significant in the aging process, and we haven't yet
really learned how to control that.
R&D © 1995 by Frederic B. Jueneman
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