Re: Prussian Blue

[JGinniver@AOL.COM]

Information on the use of Prussian Blue can be found in NCRP Report No. 65 

(Management of Persons Accidentally Contaminated with Radionuclides).



In this report the oral administration of Ferric cyanoferrate (II) commonly 

called Prussian Blue or Berlin Blue, or ferric ferrocyanide is listed as the 

most effective means of removing radioactive radiocesium in man.



This publication supports what was said by the original author of this 

thread, that it is not an approved drug (by the FDA) in the US.  It is use is 

said to reduce the biological half life to about one third of its usual 

value.  



The following are the references listed in the report for its use in man.



Mashdus, K and Stromme, A (1968) "Increased excretion of Cs-137 in humans by 

prussian blue,"  Z. Naturforsh.  23b, 391



Mashdus et al, (1966) "Diminution of radiocesium body-burden in dogs and 

human beings by prussian blue" Int. J. Biol 10, 519



Stromme, A (1968).  "Increased excretion of Cs-137 in humans," page 329 in 

Diagnosis and Treatment of Deposited Radionuclides, Korberg, H.A. and 

Norwood, W.D., Eds (Excerpta Medical Foundation Amsterdam)..



Richmond C. R. (1968). "Accelrating the turnover of internally deposited 

radiocesium". Page 315 in Diagnosis and Treatment of Deposited Radionuclides, 

Korberg, H.A. and Norwood, W.D., Eds (Excerpta Medical Foundation 

Amsterdam)..



Stather, J.W. (1972)  "Influence of Prussian Blue on metabolism of Cs-137 and 

Rb-86 in rats,"  Health Phys. 22, 1



The recommended dosage of Prussian Blue is 1 Gram orally with water 3 times 

daily for up to 3 weeks (or longer as required).  If I have read it right, 

this is the level reported to have been administered in the study by Stromme, 

1968 for up to three weeks.



One final point of interest, Radiogardase is a preperation of prussian blue 

marketed in Germany.



I hope this is of interest.

                               Julian

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