RE: WHAT'S NEW Robert L. Park Friday/UV damage

["Bjorn Cedervall" <bcradsafers@HOTMAIL.COM>]

>UV causes skin cancer but UV photons do not have enough energy to break 

>bonds, at least not directly. Does anyone know how?



Several types of photoproducts of two adjacent pyrimidines can be formed. 

The classical type - the pyrimidine dimers involves a disruption of the 

resonance structure (double bonds) in two pyrimidines next two one another. 

Then a cyclobutyl ring is formed which in turn may be repaired in several 

different ways depending on the organism. These photoproducts (which cause a 

nick in DNA) are potentially carcinogenic in mammalians.



>From my memory - please add or correct whatever needs to be done,



Bjorn Cedervall   bcradsafers@hotmail.com





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