Re: Glass-Based Radon Measurements (fwd)

[Kai Kaletsch <info@eic.nu>]

Friends,



Dr. Lagarde, one of the authors of the Glass-Based Radon-Exposure Assessment

and Lung Cancer Risk paper, has kindly commented on my previous posting. His

comment is given below. I wonder if any RadSafers would care to comment?



Personally, I don't see why one can calculate a relative risks of a combined

data set, but not odds ratios. I always thought that, given a relative risk,

one can predict what the odds ratio should be. Then the question becomes: If

the relative risk is so large, why is the odds ratio so low for high radon

exposure categories?



Best Regards,

Kai



----- Original Message -----

From: "Frederic Lagarde" <Frederic.Lagarde@imm.ki.se>

To: <epirad@mchsi.com>; "Kai Kaletsch" <info@eic.nu>; "RadSafe"

<radsafe@list.vanderbilt.edu>

Sent: Saturday, October 12, 2002 4:42 AM

Subject: Re: Glass-Based Radon Measurements (fwd)





> Dear Kai,

>

> Thank you for your interest in our study and for calculated the odds

ratios

> from the raw table data.

> However such calculations do not make sense when different studies (data

> from different centres) are combined, as is presently the case.

>

>

>

> Please, transmit a copy of this to previous recipients of your message,

and

> specify this anywhere else your previous comments appear.

>

> Sincerely,

>

> Frederic Lagarde

>

>

>

> At 15:25 2002-10-11 +0000, you wrote:

> >For your interest.  This was posted on the Radsafe

> >Radiaiton list tody.

> >----------------------  Forwarded Message:  ---------------------

> >From:    Kai Kaletsch <info@eic.nu>

> >To:      RadSafe <radsafe@list.vanderbilt.edu>

> >Subject: Re: Glass-Based Radon Measurements

> >Date:    Thu, 10 Oct 2002 15:16:50 -0600

> >

> >Friends,

> >

> >For those interested in Radon, I have calculated the odds ratios from the

> >data given in the first 2 rows of Table 4 of the Lagarde et al. paper and

> >graphed them. These rows give the number of cases and controls as a

function

> >of radon concentrations as assessed by air based and surface based

> >measurements respectively. The graph can be seen at

> >http://members.shaw.ca/eic/odds.pdf

> >Also shown on the graph (dashed lines) are the relative risks as reported

by

> >the authors.

> >

> >To me at least, it seems that the raw odds tell a different story than

the

> >RR values.

> >

> >Please let me know if I made any mistakes in calculating the odds ratios.

> >

> >Kai

> >http://www.eic.nu

> >and http://www.gammawatch.com/

> >



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