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Radiation May Help With Brain Defect
Index:
Radiation May Help With Brain Defect
House Expands Inquiry Into Fraud at Lab
Korean A-bomb survivor seeks public support in trial
North Korea could re-open nuclear plant in weeks
==============================
diation May Help With Brain Defect
DENVER (AP) Dec 16 - With the zap of a beam, 5-year-old Whitney
Boyce took a leap toward possible recovery from a brain defect that
has tyrannically worked to deprive other parts of her body of blood
since she was born.
Doctors at the University of Colorado Health Sciences Center used a
relatively new surgical device to precisely focus a high
concentration of radiation on the congenital birth defect made up of
a tangle of veins and arteries in a small portion of Whitney's brain.
With the procedure, Whitney joined a handful of patients in Colorado
treated with the Novalis Shaped Beam Surgery device, which uses beams
of photon energy aimed from several directions to target tumors or
other growths that can be stopped with radiation.
With help from computer-generated images and a system that precisely
positions the patient using grids, the radiation beams are molded to
mirror the shape and size of the growth.
``In your mind, when you hear it's radiation, it's scary. But I think
this was the best option,'' Theresa Boyce said.
The device - slightly larger than a refrigerator with a giant arm -
gave doctors the best tool available to treat Whitney's life-
threatening brain defect as well as a host of other ailments,
including brain tumors.
It could be two years before they know if the procedure worked.
Success would dramatically alter the life of the plucky kindergartner
- and ultimately may even save it.
Whitney underwent the procedure at the university's Health Sciences
Center in November.
As a newborn, she was diagnosed with an arteriovenous malformation, a
golfball-sized cluster of veins and arteries. The engorged knot
hogged blood from parts of her body, turning her blue and sending her
into congestive heart failure.
Doctors ultimately were able to pull Whitney out of heart failure,
but a new problem emerged: She went through a brief spell of
suffering seizures. The next several years were punctuated by
frequent trips to doctors and specialists who helped Whitney escape
major developmental problems. Many times it meant traveling 100 miles
to Denver from the family's home in Akron.
Much of the medical work was done by Dr. David Kumpe, director of
interventional radiology and interventional neuroradiology at the
Health Sciences Center. Kumpe, Whitney's longtime physician, has
treated the malformation with a series of non-invasive procedures in
which glue and coils were used to stem blood flow into the knot of
veins and arteries.
The work helped reduce the influence of the mass, but Kumpe said
there was a small kidney-bean sized portion remaining in a very
sensitive area. He didn't want to risk another procedure in that part
of the brain so he turned to Shaped Beam surgery.
It is designed to focus radiation and destroy blood vessels in
diseased tissue while leaving surrounding healthy tissue untouched -
a critical factor when treating the brain or other sensitive parts of
the body.
Unlike traditional open skull surgery, no incisions are made for the
Shaped Beam procedure and the treatment can be administered in just
one dose for many patients.
Experts say similar radiosurgery devices have been available for
years, but the Shaped Beam system may provide the most versatility.
``It's the best, the newest and most accurate and applicable to the
most treatment sites (on the body),'' said Timothy Solberg, director
of the medical physics division at the David Geffen School of
Medicine at the University of California at Los Angeles, where the
first patient was treated with the system in 1998.
``Up until the point of the Novalis, we couldn't shape the radiation
beam. You had to make some compromises, all of which were less than
ideal.''
``It's the first time that I've come across something in the medical
environment that's actually easier to use, but most importantly is
also better for the patient,'' he added.
Eighteen hospitals nationwide already use the device. Solberg said
UCLA alone has used the system to treat more than 1,400 brain tumor
cases.
Unlike the older Gamma Knife - which uses a super-concentrated beam
of radiation - the Shaped Beam system does not have a radioactive
source that has to be replaced. It uses electricity.
``I think it's the future for radiosurgery because it can be used for
many purposes,'' said Dr. Laurie Gaspar, chair of the department of
radiation oncology at the Health Sciences Center.
If left untreated, the malformation afflicting Whitney has a 95
percent mortality rate.
With the Shaped Beam surgery, Whitney's prognosis is very good, Kumpe
said, adding that he hoped most of the mass had dried up.
``If we do an angiogram in two years, it may show that she may need
to get more treatment,'' he said.
Within two days of the procedure, Whitney was home, demanding to be
allowed to attend her kindergarten, insisting her presence was
required because it was her day to bring classmates a snack.
On the Net:
http://www.uch.edu
http://www.brainlab.com
-----------------
House Expands Inquiry Into Fraud at Lab
WASHINGTON (AP) - A House committee is expanding its inquiry into
allegations of fraud and credit card abuse at Los Alamos National
Laboratory. A letter from the committee said abuse appears more
widespread than thought.
The committee issued a sweeping demand for new documents, including
reports on the alleged irregularities to lab director John C. Browne
and a breakdown of whether computers missing from the nuclear lab
contained classified information.
Ken Johnson, the committee spokesman, said three investigators were
being sent to the lab and will begin work on Monday.
``It is apparent that the amount of fraud and abuse at LANL is much
more extensive and includes many more employees than we had
originally at first believed,'' said the letter, signed by the
committee chairman, Rep. Billy Tauzin, R-La., and other senior
committee members.
The letter to Richard Atkinson, president of the University of
California, which runs the lab, expressed frustration at ``the
apparent failure of the University of California and LANL to
sufficiently address these issues over the past several years.''
The letter was sent Tuesday and distributed Friday.
It requested documents regarding the departure of two investigators
fired after blowing the whistle on the lab's management practices and
also demanded materials from PricewaterhouseCoopers, the lab's
auditor.
Johnson said the expanded request for documents was a result of
questions raised by papers received from an earlier committee
request, press reports and information from Los Alamos employees
``suggesting that the problems are more prevalent than first
reported.''
Danielle Brian, executive director of the Washington-based watchdog
group Project on Government Oversight, which has worked with Los
Alamos whistle-blowers, said the letter was an encouraging sign.
``We think it's a great start. It's obviously a serious
investigation,'' she said.
The Los Alamos lab grew out of the Manhattan Project that developed
the atomic bomb during World War II and has been a vital part of the
country's nuclear energy and weapons programs since.
The FBI, the Energy Department's inspector general and the Senate
Finance Committee also are investigating the allegations of fraud,
theft and cover-up at the nuclear weapons lab. Three lab employees
are on administrative leave following initial phases of the
investigation.
Two investigators, Glenn Walp and Steven Doran, who reported misuse
of credit cards and missing equipment - some from sensitive areas of
the lab - were fired.
Walp submitted a report to Los Alamos authorities in March that
listed 263 computers as missing since 1999, many presumed stolen. In
all, about $2.7 million worth of equipment is unaccounted for,
according to Walp's reports.
On Oct. 31, FBI agents carrying search warrants scoured the homes of
Los Alamos employees Peter Bussolini and Scott Alexander and found
thousands of dollars worth of goods that may have been acquired by
abusing lab purchase orders.
A third employee may have used her government credit card to buy a
Ford Mustang with custom equipment.
On the Net: Los Alamos National Laboratory: http://www.lanl.gov
House Energy and Commerce Committee: http://www.house.gov/commerce/
----------------
Korean A-bomb survivor seeks public support in trial
HIROSHIMA, Dec. 14 (Kyodo) - A Korean survivor of the 1945 U.S.
atomic bombing of Hiroshima who won a healthcare damages suit in a
Dec. 5 high court ruling on Saturday asked for public support in
trying to persuade the government not to appeal to the Supreme Court.
''I think the ruling coalition is moving in the right direction of
giving up appealing,'' Kwak Kwi Hoon, 78, told a news conference in
the city of Hiroshima. ''Hiroshima is a central place for A-bomb
survivor issues. Please exert strong influence.''
The Osaka High Court rejected the state's appeal of the June 2001
Osaka District Court ruling and ordered the central and Osaka
prefectural governments to pay Kwak compensation, including
retroactive payments.
''The reasoning of bureaucrats was completely turned down in the high
court ruling. There is no more legitimate reason and it is unlikely
that they can win in similar trials,'' Kwak said. ''If they have
common sense, they will not appeal.''
Kwak has stayed in Japan since the ruling to call on the government
to give up appealing to the Supreme Court.
It was the first high court ruling in Japan to recognize that atomic
bomb survivors who have received an A-bomb survivor's health card but
live abroad are eligible to receive the allowance based on the Atomic
Bomb Victims Relief law on the same terms as those living in Japan.
Osaka Gov. Fusae Ota has suggested she will accept the high court
ruling, while Health minister Chikara Sakaguchi hinted Friday he does
not intend to appeal.
According to the high court ruling, Kwak was drafted by the Imperial
Japanese Army in September 1944 and was serving in Hiroshima when the
United States dropped the atomic bomb on it Aug. 6, 1945.
After World War II, he went to South Korea, but returned to Japan in
1998 to receive medical treatment. He received 34,000 yen per month
in medical allowances for two months that year, but the Osaka
prefectural government stopped payments after he returned to South
Korea in July in 1998.
On Saturday in the city of Fukuoka, Byong Yong Ok, vice chairman of a
South Korean association for atomic bombing survivors, also called on
the government not to appeal.
Speaking at a lecture, Byong said, ''The number of atomic survivors
is falling every year as they are getting old. They were bombed as
Japanese citizens. It isn't too late. Please save them.''
Byong was exposed to radiation when he was 10 in Hiroshima. Byong,
who returned to South Korea, was the first A-bomb survivor abroad to
receive medical treatment at a Japanese hospital in 1975.
Byong was invited to Japan by a Fukuoka theater group that has
organized plays related to A-bomb survivors.
------------------
North Korea could re-open nuclear plant in weeks
SEOUL, Dec 13 (Reuters) - North Korea could crank up a mothballed
nuclear plant at the centre of a suspected arms programme in a couple
of months, but it would do little to solve the communist state's fuel
crisis, analysts said on Friday.
Pyongyang said on Thursday it was reactivating a Soviet-built nuclear
energy research complex at Yongbyon, raising the stakes in a stand-
off at the world's last Cold War flashpoint.
The International Atomic Energy Agency (IAEA) said North Korea had
asked it to unseal and remove surveillance cameras from the plant,
closed in 1994 after Pyongyang agreed with Washington to freeze its
nuclear programme in exchange for free energy.
Facing another harsh winter, a North Korean Foreign Ministry
spokesman said the country had no choice but to revive the Yongbyon
complex for critically needed power after Washington and its allies
cut off free oil shipments for North Korea last month.
But the decision to fire up a tiny five-megawatt reactor is hardly a
solution to the reclusive communist state's energy shortage that has
shut down factories and condemned most of its 22 million people to
huddling in dark, cold homes this winter.
"It's almost nothing," said Chang Sun-sup, South Korea's chief
representative to the Korea Energy Development Organisation, charged
with implementing the 1994 "Agreed Framework." He said it would take
"about one to two months' to restart the plant.
SYMBOLIC REOPENING
"It's a symbolic reopening," Chang told Reuters. "But if they operate
the reactor, they can burn uranium and extract spent fuel from the
reactor."
That's what North Korea did on at least three occasions between 1989
and 1991, according to the IAEA. Western intelligence agencies
suspect North Korea reprocessed enough plutonium for one or two
atomic bombs.
In October this year North Korea finally acknowledged a programme to
produce highly enriched uranium, a key ingredient in nuclear weapons.
That admission prompted the United States and its allies to suspend
the fuel oil shipments in a bid to force Pyongyang to abandon its
nuclear arms programme.
The North was promised a $5 billion package under the 1994 deal,
including two "safe" light water reactors and 500,000 tonnes annually
of heavy fuel oil to power its creaking Soviet-built factories.
The shipments accounted for 15 percent of the total power output in
North Korea, where power plants are only operating at 20-30 percent
capacity, South Korean officials said.
The light water reactors are still under construction.
"Obviously they have a huge energy crisis," said a Beijing-based aid
worker who visits North Korea frequently. "You drive through the
countryside there after dark, through huge cities beyond Pyongyang,
and you don't see a bulb."
The Yongbyon complex, near the northwest city of Taechon, also
includes a partially completed 50-megawatt plant whose construction
was halted under the 1994 pact. An IAEA official once described the
plant as "extremely primitive" and far from ready to produce
plutonium on an industrial scale.
NEGOTIATING PLOY
Ralph Cossa, president of Pacific Forum CSIS, said it would take
about a year of running the five-megawatt reactor before it can
produce spent fuel that can be processed into plutonium.
"So there is no sense of urgency," he said.
"My guess is this is a ploy to get us back to the table or to
frighten others to pressure us to return to negotiations, which also
indicates that they are feeling the pressure from the international
community," Cossa said.
The Yongbyon complex also contains three nuclear waste storage sites,
including one designated "Building 500" by the CIA that became
operational in 1990 and is one of North Korea's suspect undeclared
nuclear facilities, according to the Center for Nonproliferation
Studies in Northern California.
North Korea is also believed to be conducting uranium enrichment
tests at three other sites, South Korea media have reported.
The head of the Federation of Red Cross and Red Crescent Societies in
North Korea, Per Gunnar Jenssen, told Reuters by telephone from
Pyongyang he had seen a slight improvement in the electricity crisis
earlier this year.
"My observation is that there have been more trucks on the roads this
autumn than the autumn before, and there has been more trains moving
around with coal for instance, and this has led to some improvements
which the Koreans I have spoken to are fearing could be reversed
again."
-------------------------------------------------
Sandy Perle
Director, Technical
ICN Worldwide Dosimetry Service
ICN Plaza, 3300 Hyland Avenue
Costa Mesa, CA 92626
Tel:(714) 545-0100 / (800) 548-5100 Extension 2306
Fax:(714) 668-3149
E-Mail: sandyfl@earthlink.net
E-Mail: sperle@icnpharm.com
Personal Website: http://sandy-travels.com/
ICN Worldwide Dosimetry Website: http://www.dosimetry.com/
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