Dear
Colleagues,
In regard to
chemical agents used for treating certain types of RAM exposures, are there any
substitutes available for the following two chemicals ?
Ferric ferrocyanide (Prussian Blue),
a blocking agent for Cs-137, is not recognized by the U.S. Pharmacopeia and is
not approved by the FDA.
DTPA, a chelating agent, is not
commercially available either. I believe it is only available under
Investigational New Drug (IND) permits for treatment of persons contaminated
internally with plutonium. However, calcium EDTA is available and has
effectiveness for the transuranium metals, but DTPA is generally more
effective.
Any assistance
or direction would be appreciated. Thank you.
David
Engelbretson
Radiation Safety
Dept.
Methodist
Hospital, Houston, Texas