DOE is looking for researchers to do low dose radiation studies and modeling. The original Federal Register posting http://www.access.gpo.gov/su_docs/aces/aces140.html and supply the appropriate dates and other identificating information.
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Federal Register: February 19, 2003 (Volume 68,
Number 33).
Section: Notices
Agency: DEPARTMENT OF ENERGY
Title: Office of Science Financial Assistance
Program Notice 03-20; Low Dose Radiation
Research Program--Biologically-Based Risk
Modeling
Action: Notice inviting applications.
Page: 7988-7989
DEPARTMENT OF ENERGY
Office of Science Financial Assistance Program Notice
03-20; Low Dose Radiation Research
Program--Biologically-Based Risk Modeling
AGENCY: Department of Energy.
ACTION: Notice inviting applications.
SUMMARY: The Office of Biological and Environmental
Research (OBER) of the Office of Science (SC), U.S.
Department of Energy (DOE), hereby announces its
interest in receiving applications for participation in
a biologically-based risk modeling exercise, for the
purposes of developing! and evaluating different
modeling/prediction strategies. Awardees will be asked
to develop individual biologically-based models
incorporating one or more phenomena such as adaptive
response, bystander effects, genetic susceptibility, or
genomic instability. A central aspect of this exercise
will be the eventual modeling, by all awardees, of an
artificially defined biological test system or
archetype having a set of biological characteristics
and radiation-induced endpoints for which exact
probability values are either known or assigned. Please
review the Supplementary Information and Application
sections below for further details.
DATES: Preapplications (letters of intent) should be
submitted by April 4, 2003. Formal applications are due
4:30 p.m. EDT, May 23, 2003, in order to be accepted
for merit review and to permit timely consideration for
award in Fiscal Year 2003.
ADDRESSES: Preapplications referencing Progr! am Notice
03-20, should be sent to Ms. Joanne Corcoran by E-mail:
joanne.corcoran@science.doe.gov , with a copy to Dr.
Noelle Metting at: noelle.metting@science.doe.gov .
Formal applications referencing Program Notice 03-20
must be sent electronically by an authorized
institutional business official through DOE's Industry
Interactive Procurement System (IIPS) at:
http://e-center.doe.gov
(see also
http://www.sc.doe.gov/production/grants/grants.html ).
IIPS provides for the posting of solicitations and receipt
of applications in a paperless environment via the
Internet. In order to submit applications through IIPS
your business official will need to register at the IIPS
website. The Office of Science will include attachments as
part of this notice that provide the appropriate forms in
PDF fillable format that are to be submitted through IIPS.
Color images should be submitted in IIPS as a separate
file i! n PDF format and identified as such. These images
should be kept to a minimum due to the limitations of
reproducing them. They should be numbered and referred
to in the body of the technical scientific application
as Color image 1, Color image 2, etc. Questions
regarding the operation of IIPS may be E-mailed to the
IIPS Help Desk at: HelpDesk@pr.doe.gov, or you may call
the help desk at: (800) 683-0751. Further information
on the use of IIPS by the Office of Science is
available at:
http://www.sc.doe.gov/production/grants/grants.html .
If you are unable to submit the application through IIPS,
please contact the Grants and Contracts Division, Office
of Science at: (301) 903-5212, in order to gain
assistance for submission through IIPS or to receive
special approval and instruction on how to submit printed
applications.
FOR FURTHER INFORMATION CONTACT: Dr. Noelle Metting,
telephone: (301) 903-8309, E-mail:
noel! le.metting@science.doe.gov , Office of Biological and
Environmental Research, U.S. Department of Energy,
SC-72/Germantown Building, 1000 Independence Avenue, SW.,
Washington, DC 20585-1290.
SUPPLEMENTARY INFORMATION: The Low Dose Radiation
Research Program has the challenge of conducting research
that can be used to inform the development of future
national radiation risk policy for the public and the
workplace. The Program has focused on quantifying and
understanding the mechanisms of molecular and cellular
responses to low dose exposures to radiation, currently
0.1 Gy (10 rads) or less, with a view toward the lower
doses. Most scientists in the field would agree that not
enough is yet known about the biological consequences of
low dose radiation exposure to be able to completely
model human health risk. However, it is timely to begin
to systematically evaluate different approaches for
modeling the diversity of available ! information on the
biological effects of low dose radiation exposure.
. . .