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RE: Re: AAP Statement on Radiation Disasters and Children[Scanned]



Potassium iodide, potassium iodate, and calcium iodate are all

recognized as safe food additives by the FDA.  Various forms of

potassium iodide are approved as drugs, either prescription or over

the counter.



They all are capable providing enough iodine to block the uptake of

radioactive iodine.  Some sources state that as little as 6 mg. of

absorbed iodine will block uptake.



Solubility:

Potassium iodide 1gm./0.7ml water

Potassium iodate 1gm./12 ml water

Calcium iodate   approximately 1gm./100 ml water



Speed of onset:

Due to solubility potassium iodide faster than potassium iodate which

is faster than calcium iodate.



Effective shelf life:

In sealed containers, protected from light and humidity, they are all

very stable (years).  Once opened Calcium iodate is the most stable,

next is potassium iodate, least is potassium iodide.



Toxicity:

Anyone sensitive to iodine should consult a physician prior to taking

any of these products. Patients taking Lithium salts should not take

these products. Anyone taking potassium sparing diuretics or

potassium supplements should not take the potassium products. Anyone

taking antithyroid agents should consult a physician prior to taking

any of these products.

The Iodates have the advantage of being practically tasteless but

because they are oxidizing agents they can cause some gastric upset.

Potassium iodide can also cause some gastric discomfort.

Taking any of these products with food and lots of liquids solves the

problem.



Dosage:



Potassium iodide  130 mg provides approx 100 mg. iodine



Potassium iodate  170 mg provides approx 100 mg. iodine



Calcium iodate    154 mg provides approx 100 mg. iodine



Hope this helps.



John K.



---- Original Message ----

From: chofmeyr@nnr.co.za

To: jkuperus@custompharmacy.com

Subject: RE: Re: AAP Statement on Radiation Disasters and

Children[Scanned]

Date: Thu, 10 Apr 2003 13:09:09 +0200



>Could someone please explain the relative properties of KI (potassium

>iodide) and potassium iodate tablets as thyroid blockers in terms of

>dosage, speed of uptake, toxicity, effective shelf life, etc.

>Chris Hofmeyr

>chofmeyr@nnr.co.za

>

>-----Original Message-----

>From: jkuperus@custompharmacy.com

>[mailto:jkuperus@custompharmacy.com]

>Sent: 09 April 2003 04:17

>To: radsafe@list.vanderbilt.edu

>Subject: FW: Re: AAP Statement on Radiation Disasters and

>Children[Scanned]

>

>Could not resist. This is also in reply to Shane Connor.

>

>Daily intake of free iodine = 0.0001 gm.

>

>Total body content = 0.01 gm.

>

>Uptake of radioactive iodine can be suppressed by any stable iodine

>source which can flood the bodies iodine pool. As documented by

>their....

>Etc.







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