Re: Get your tickets now - New Discussion List

[maury]

Jerry, I hope you will bring the answer back to Radsafe. I. too. would like to know

exactly what is meant by unbounded residual confounding -- regardless of the

particular experimental context for the term. I assume it is not something completely

peculiar to smoking or radon research. Just as a factor in experimental design and

analysis, I'd like to know.

Thanks in advance,

Maury Siskel     maury@webtexas.com

=========================

niton@mchsi.com wrote:



> Jerry, I would happy to respond to that question, but please move it over to

> the other list.

>

> To join the list, go to: http://list.uiowa.edu/archives/radhealth.html

>

>  Regards, Bill

> > To help those of us who may not be among the cognoscenti, could someone

> > please explain the concept of  " unbounded residual confounding ". Could this

> > phenomenon also account for the apparently positive association between

> > smoking and cancer?

> >

> >

> > ----- Original Message -----

> > From: <niton@mchsi.com>

> > To: BERNARD L COHEN <blc+@PITT.EDU>

> > Cc: 'Radiation Safety' <radsafe@list.vanderbilt.edu>; <RADHEALTH@LIST.UIOWA.EDU>

> > Sent: Friday, July 04, 2003 11:25 AM

> > Subject: Get your tickets now - New Discussion List

> >

> >

> > > Dr. Cohen,

> > >

> > > Many people have offered suggestions to help you with your plea to explain

> > > your inverse associations we all see with your ecologic data.

> > >

> > > As Edward Teller sated, Two paradoxes are better than one; they may even

> > > suggest a solution.

> > >

> > > I believe Dr. Teller's statement is very applicable to our discussion.

> > >

> > > Paradox 1: Your well known inverse association between smoking and lung

> > cancer.

> > >

> > > Paradox 2: The less than well known inverse association between your county

> > > radon data and other smoking related cancers.

> > >

> > > The existence of these two paradoxes helps to explain that the cause of these

> > > inverse associations are merely unbounded residual confounding from smoking

> > and other within county variables associated with smoking

> >

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