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" New Way of 'Seeing': A 'Neutron Microscope' "
http://www.physorg.com/news599.html
New Way of 'Seeing': A 'Neutron Microscope'
July 30, 2004
A prototype microscope that uses neutrons instead of light to "see"
magnified images has been demonstrated at the National Institute of
Standards and Technology (NIST). Neutron microscopes might eventually offer
certain advantages over optical, X-ray and electron imaging techniques such
as better contrast for biological samples.
Described in the July 19 issue of Applied Physics Letters,* the imaging
process involves hitting a sample with an intense neutron beam. The neutrons
that pass through.whose pattern reflects the sample.s internal structure.are
directed into a row of 100 dimpled aluminum plates. Each dimpled plate acts
like a weak focusing lens for neutrons, diverting the neutrons. path
slightly at each interface. The image then is projected onto a detector.
Adelphi Technology Inc. of San Carlos, Calif., designed and demonstrated the
microscope with the help of NIST scientists, who routinely use multiple
lenses to focus neutron beams for other research.
In principle, neutrons could provide better image resolution than visible
light because they have shorter wavelengths.as short as 1 nanometer (nm)
compared to 400-700 nm. In this demonstration at NIST.s Center for Neutron
Research, the microscope produced a resolution of only 0.5 millimeters and a
magnification of about 10. However, Adelphi hopes to substantially improve
image resolution through research to reduce lens aberrations. The company
also hopes to build a compact, laboratory-scale neutron source.
Moreover, neutrons offer some unique advantages. Unlike other imaging
methods, neutrons interact strongly with hydrogen, an important component of
biological samples composed mostly of hydrocarbons and water. And neutrons
easily penetrate samples, thereby reducing artifacts produced with other
techniques requiring thin slices, staining or fixing.
Stanford University also participated in the research, which was supported
in part by the U.S. Department of Energy.
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