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AW: Radiolabeling
Franz Schoenhofer
PhD, MR iR
Habicherg. 31/7
A-1160 Vienna
AUSTRIA
phone -43-0699-1168-1319
I do not really know, whether you are looking for tracer application or
real labelling of organic molecules with I-131, T, C-14 etc.
Regarding tracer application Ben has correctly stated Georg Hevesy's
contribution. I would like to add an anecdote, which I have been assured
is not fiction, but true.
When Hevesy lived at the town where he did his experiments (it might
have been Vienna!) he was suspicious that the landlady of the place he
lived used the remains from dinner to prepare next days dinner. So he
added some radioactive material to the remains of his dinner plate - and
found next days dinner to be radioactive. He immediately changed his
lodging......
Best regards,
Franz
> -----Ursprüngliche Nachricht-----
> Von: owner-radsafe@list.vanderbilt.edu [mailto:owner-
> radsafe@list.vanderbilt.edu] Im Auftrag von Morgan, Ben
> Gesendet: Montag, 15. November 2004 20:01
> An: Jean-Francois, Stephane; radsafe@list.vanderbilt.edu
> Betreff: RE: Radiolabeling
>
> Greetings:
>
> A reference I enjoyed reading is "Radiochemistry and Nuclear Methods
of
> Analysis" by William D. Ehmann and Diane E Vance. [Published by John
Wiley
> & Sons, Inc. ISBN 0-471-60076-8 or 0-471-30628-2]
>
> In Chapter 10 the book states that Georg Hevesy is credited with
> originating the use of radionuclides as tracers. In 1913 he was using
> radium-D (Pb-210) to determine the solubility of lead salts in water.
He
> was also the first to use radionuclides to study biological processes
in
> plants and animals. He received the Nobel Prize for this work in 1943.
>
> Regards,
>
> Ben
>
> ben.morgan@pgnmail.com
>
>
> -----Original Message-----
> From: owner-radsafe@list.vanderbilt.edu [mailto:owner-
> radsafe@list.vanderbilt.edu] On Behalf Of Jean-Francois, Stephane
> Sent: Monday, November 15, 2004 1:00 PM
> To: 'radsafe@list.vanderbilt.edu'
> Subject: Radiolabeling
>
>
> I am interested in the "little history" of radiolabeling in University
and
> bioresearch area. Anyone have interesting reference, I would like to
have
> an idea of WHEN people have started to label with radioactive
material.
>
> Thanks in advance.
>
> Stéphane Jean-François, Eng., CHP
> Spécialiste en radioprotection/Health Physics specialist Gestion des
> risques/Risk Management Centre de recherche thérapeutique de Merck
> Frosst/Merck Frosst Center for Therapeutic Research 514-428-8695
> FAX: 514-428-8670
> stephane_jeanfrancois@merck.com
> www.merckfrosstlab.ca <www.merckfrosstlab.ca>
>
>
>
>
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