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RE: U-232 retention in bone (was Re: Reply to James Salsman)
James et al
"BNWL" is Battelle NorthWest Laboratory, the old name for Battelle Pacific
Northwest National Laboratory, or PNNL. When I worked there it was PNL. The
second N was added in the '90's.
John
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-----Original Message-----
From: owner-radsafe@list.vanderbilt.edu
[mailto:owner-radsafe@list.vanderbilt.edu]On Behalf Of James Salsman
Sent: December 20, 2004 1:35 PM
To: marktwain403@YAHOO.COM
Cc: du-list@yahoogroups.com; radsafe@list.vanderbilt.edu
Subject: U-232 retention in bone (was Re: Reply to James Salsman)
>... You say also that U-232 "doesn't clear up over
> time like the other isotopes". Really? Because U-232 is uranium,
> it is expected to behave almost identically to all the other
> isotopes of uranium. Where did you get the information that it
> behaves differently?
The Gmelin Handbook of Inorganic Chemistry, 8th Edition, English
translation (Springer-Verlag, 1982), Title U -- Uranium, Supplemental
Volume A7 -- Biology, Section 3 -- Metabolism: Absorption, page 305,
Figure 3-1, "Retention and translocation of inhaled uranyl nitrate,"
from J.E. Ballou, R.A. Gies, and N.A. Wagman, in "BNWL-2500," Part 1,
pp. 379-380 (1978.)
The graph shows the skeletal load of U-232 growing from 19% of the
initial lung burden five days after exposure up to 25% after 200
days. In contrast, the skeletal U-233 load falls from 20% after
five days down to 5% after 200 days. Both isotopes clear from the
lung after initial exposure, and kidney concentrations of both
isotopes also drop from their levels five days after exposure.
Different isotopes of an element can influence chemical reactions,
via thermodynamic properties, according to Encyclopedia Britannica:
http://www.britannica.com/eb/article?tocId=48262
Sadly, I did not copy the Gmelin reference abbreviations, so I can
not say what "BNWL" stands for. However, perhaps you can reach the
authors through the Health Physics Society, as the first two appear
in Health Phys. 1978 May;34(5):445-50, "The influence of DTPA on
the biological availability of transuranics," by J.E. Ballou,
K.R. Price, R.A. Gies, and P.G. Doctor.
Sincerely,
James Salsman
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